Recombinant Human YWHAQ protein, MYC/DDK-tagged

• Cat.No.: YWHAQ-123H
• Product Overview: Recombinant Human YWHAQ fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 27.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta [ Homo sapiens ]
• Official Symbol: YWHAQ
• Synonyms: 1C5; HS1; 14-3-3; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
• Gene ID: 10971
• mRNA Refseq: NM_006826
• Protein Refseq: NP_006817
• MIM: 609009
• UniProt ID: P27348
• Chromosome Location: 2p25.1
• Pathway: Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Apoptosis, organism-specific biosystem
• Function: protein N-terminus binding; protein binding; protein domain specific binding