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5-Lipoxygenase Inhibitor Screening Kit (Fluorometric)

Cat.No.: Kit-2318
Product Overview: 5-Lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase that converts unsaturated fatty acids to epoxides; for example the synthesis of leukotrienes from arachidonic acid. It is involved in processes like cell proliferation, differentiation and inflammation and has been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer. Research for identifying potential remedies for such diseases involves the identification of inhibitors of 5-lipoxygenase. 5-Lipoxygenase Inhibitor Screening Kit uses Zileuton, a well-known 5-lipoxygenase inhibitor as positive control, and provides a simple and fast method to screen/ characterize potential 5-lipoxygenase inhibitors.
Applications: Screening of potential inhibitors of 5-lipoxygenase
Storage: -20°C
Shipping: Gel Pack
Size: 100 assays
Kit Components: LOX Assay Buffer; LOX Probe; LOX Substrate; Zileuton; 5-LOX Enzyme
Target Species: Human
Detection method: Fluorescence (Ex/Em 500/536 nm)
Features & Benefits: Simple procedure; takes only ~40 min; Fast and convenient

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