Active Native Canine Follicle Stimulating Hormone(FSH) protein
Cat.No. : | FSH-031C |
Product Overview : | Native Canine Follicle Stimulating Hormone(FSH) was purified from Canine Pituitary Glands. |
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Description : | Follicle stimulating hormone (FSH) is a hormone synthesised and secreted by gonadotropes in the anterior pituitary gland. In the ovary FSH stimulates the growth of immature Graafian follicles to maturation. FSH is a glycoprotein secreted by the basophil cells of the anterior pituitary. Gonadotropin-releasing hormone (GnRH), produced in the hypothalamus, controls the release of FSH from the anterior pituitary. Like other glycoproteins, such as LH, TSH, and HCG, FSH consists of subunits designated as alpha and beta. Hormones of this type have alpha subunits that are very similar in structure; therefore the biological and immunological properties of each hormone are dependent on the unique beta subunit. In the female, FSH stimulates the growth and maturation of ovarian follicles by acting directly on the receptors located on the granulosa cells; follicular steroidogenesis is promoted and LH production is stimulated. |
Source : | Canine Pituitary Glands |
Species : | Canine |
Form : | Lyophilized powder |
Bio-activity : | ≥0.1 x NIH-FSH-S1 |
Storage : | 2 ℃ to 8 ℃ |
Products Types
◆ Recombinant Protein | ||
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FSH-5822A | Recombinant Chinese sturgeon FSH Protein (Met1-Asp128), C-Fc tagged | +Inquiry |
FSH-01H | Recombinant Human FSH protein | +Inquiry |
FSH-129H | Active Recombinant Human Follicle Stimulating Hormone protein | +Inquiry |
◆ Native Protein | ||
FSH-35H | Native Human Follicle Stimulating Hormone | +Inquiry |
FSH-1566P | Active Native Porcine Stimulating Hormone | +Inquiry |
FSH-93P | Active Native Porcine FSH | +Inquiry |
Not For Human Consumption!
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Customer Reviews (5)
Write a reviewHigh efficiency for horseradish peroxidase labeling.
Successfully used for Pull-down assay.
Useful in biolayer interferometry.
Useful in computational and crystallographic studies.
Good for Co-IP control.
Q&As (10)
Ask a questionlipid metabolism pathways were significantly enriched in DEGs among 3 follicular development stages in FSH superstimulation.
Structural similarity with other glycoprotein hormones of pituitary and placental origin such as luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and human choriogonadotropin hormone (hCG).
These glycoforms have been shown to have differential functional effects in in vitro studies.
FSH-FSHR signaling can promotes angiogenesis.
FSH has been identified to stimulate release of IL-1ß, which increases the length of survival time of osteoclasts causing further bone resorption to occur.
Accumulating body of evidence demonstrates that FSHR is expressed in different types of tumors, such as: prostate, ovarian, thyroid, neuroendocrine, pancreatic, pituitary, and soft tissue sarcomas.
Biological functions of FSH are activated through its interaction with its specific receptors (i.e. FSHR1).
Functional specificity of FSH is provided by its β-subunit that ensures FSH interaction specifically with FSH receptor (FSHR).
FSH is a glycoprotein and plays an important role in: growth, development, pubertal maturation, and reproductive physiology.
Gonadotrophs of the anterior pituitary gland synthesize and secrete follicle stimulating hormone (FSH) in response to stimulation by the hypothalamic gonadotropin releasing hormone.
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