Active Recombinant Full Length Human LBP Protein
Cat.No. : | LBP-10HFL |
Product Overview : | Recombinant Full Length Human LBP Protein without tag was expressed in Mouse myeloma cell line. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). |
Source : | Mouse myeloma cell line |
Species : | Human |
Tag : | Tag Free |
Bio-activity : | Measured by its ability to enhance LPS-stimulated IL-8 secretion by THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 0.25-2.5 ng/mL. |
Molecular Mass : | Predicted Molecular Mass: 51 kDa SDS-PAGE: 55-60 kDa, reducing conditions |
Protein Length : | Full Length |
N-terminal Sequence Analysis : | Ala26 |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and EDTA with BSA as a carrier protein. |
Reconstitution : | Reconstitute at 50 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | LBP lipopolysaccharide binding protein [ Homo sapiens (human) ] |
Official Symbol : | LBP |
Synonyms : | LBP; lipopolysaccharide binding protein; BPIFD2; lipopolysaccharide-binding protein; BPI fold containing family D, member 2; LPS-binding protein |
Gene ID : | 3929 |
mRNA Refseq : | NM_004139 |
Protein Refseq : | NP_004130 |
MIM : | 151990 |
UniProt ID : | P18428 |
Products Types
◆ Recombinant Protein | ||
LBP-3338H | Recombinant Human LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-5008M | Recombinant Mouse LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-821H | Recombinant Human LBP Protein | +Inquiry |
Lbp-5009M | Recombinant Mouse Lbp Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-007H | Recombinant Human LBP Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LBP-1853HCL | Recombinant Human LBP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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