Recombinant Human Lipopolysaccharide Binding Protein, His-tagged
Cat.No. : | LBP-4927H |
Product Overview : | Recombinant human LBP containing His tag was expressed by baculovirus in CHO cells and having a molecular mass of 58.0 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | LBP-4927H |
Description : | Natural LBP is a 58 kDa glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophils and granulocytes. This is a His-tagged protein |
Biological Activity : | Up to 0.2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (FACS). |
Molecular Weight : | 58.0 kDa |
Source : | CHO cells |
Species : | Human |
Form : | Lyophilized from a concentrated protein solution (0.25mg/ml) containing PBS, pH 7.2 |
Endotoxin Level : | < 0.03 ng/ ml |
Appearance : | Lyophilized protein |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in 40 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at -20°C or -70°C for future use. |
Purity : | >90-95% by SDS-PAGE analyses |
Storage : | The lyophilized protein is best-stored desiccated below 0°C. Reconstituted protein should be used immediately or stored in undiluted working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% BSA). Repeated freezing and thawing should be avoided. |
Pathways : | Toll-like receptor signaling pathway; Signaling in Immune system |
Gene Name : | LBP lipopolysaccharide binding protein [ Homo sapiens ] |
Official Symbol : | LBP |
Synonyms : | LBP; lipopolysaccharide binding protein; BPIFD2; MGC22233; lipopolysaccharide-binding protein; OTTHUMP00000030965; LPS-binding protein; BPI fold containing family D, member 2 |
Gene ID : | 3929 |
mRNA Refseq : | NM_004139 |
Protein Refseq : | NP_004130 |
MIM : | 151990 |
UniProt ID : | P18428 |
Chromosome Location : | 20q11.23-q12 |
Function : | Gram-negative bacterial cell surface binding; Gram-positive bacterial cell surface binding; cell surface binding; lipid binding; lipopolysaccharide binding; lipoteichoic acid binding; receptor binding |
Products Types
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LBP-3338H | Recombinant Human LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-007H | Recombinant Human LBP Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LBP-1853HCL | Recombinant Human LBP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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