Active Recombinant Human ACE2 Protein, His\Avi-tagged
Cat.No. : | ACE2-208H |
Product Overview : | Biotinylated Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a Avi, 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
Source : | Human Cells |
Species : | Human |
Tag : | His\Avi |
Form : | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4. |
Bio-activity : | Immobilized 2019-nCoV S Protein RBD-SD1-mFc at 2μg/ml (100μl/well) can bind Human ACE-2-Avi-His.The ED50 of Human ACE-2-Avi-His is 46.47 ng/ml. |
Molecular Mass : | Predicted Molecular Weight: 86.2kDa Apparent Molecular Weight: 110-140kDa, reducing conditions. |
AA Sequence : | Gln18-Ser740 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >95% |
Storage : | Store at < -20 centigrade, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Quality Statement : | Purity: greater than 95% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | ACE2 angiotensin converting enzyme 2 [ Homo sapiens (human) ] |
Official Symbol : | ACE2 |
Synonyms : | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE-2 |
Gene ID : | 59272 |
mRNA Refseq : | NM_021804.3 |
Protein Refseq : | NP_068576.1 |
MIM : | 300335 |
UniProt ID : | Q9BYF1 |
Products Types
◆ Recombinant Protein | ||
Ace2-35R | Recombinant Rat Ace2 Protein, His-tagged | +Inquiry |
ACE2-2413H | Recombinant Human ACE2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ace2-603R | Active Recombinant Rat ACE2 Protein, Fc-tagged | +Inquiry |
ACE2-0464H | Recombinant Human ACE2 Protein (M1-S740), Tag Free | +Inquiry |
ACE2-10H | Active Recombinant Human ACE2 Protein, FLAG-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
ACE2-887CCL | Recombinant Cynomolgus ACE2 cell lysate | +Inquiry |
ACE2-3100HCL | Recombinant Human ACE2 cell lysate | +Inquiry |
ACE2-2085MCL | Recombinant Mouse ACE2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2101 | Angiotensin II Converting Enzyme Inhibitor Screening Kit | +Inquiry |
Kit-2210 | Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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