Active Recombinant Human BLK, GST-tagged
Cat.No. : | BLK-1366H |
Product Overview : | Recombinant full-length human BLK was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells. Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 112 nmol/min/mg |
Molecular Mass : | ~84 kDa |
Protein length : | Full length |
Purity : | >90% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | BLK B lymphoid tyrosine kinase [ Homo sapiens ] |
Official Symbol : | BLK |
Synonyms : | BLK; B lymphoid tyrosine kinase; tyrosine-protein kinase Blk; MGC10442; p55-Blk; b lymphocyte kinase; BLK nonreceptor tyrosine kinase; MODY11; |
Gene ID : | 640 |
mRNA Refseq : | NM_001715 |
Protein Refseq : | NP_001706 |
MIM : | 191305 |
UniProt ID : | P51451 |
Chromosome Location : | 8p23-p22 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; EPHA forward signaling, organism-specific biosystem; |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
BLK-0746H | Recombinant Human BLK Protein (G2-P505), GST tagged | +Inquiry |
BLK-01H | Recombinant Human BLK Protein, His-tagged | +Inquiry |
BLK-5368H | Recombinant Human B Lymphoid Tyrosine Kinase, His-tagged | +Inquiry |
BLK-0745H | Recombinant Human BLK Protein (G2-P505), Tag Free | +Inquiry |
BLK-1039M | Recombinant Mouse BLK Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BLK-614HCL | Recombinant Human BLK cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1566 | BLK Activity Assay Kit | +Inquiry |
Kit-1565 | BLK Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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