Active Recombinant Human NTN1 protein, His-tagged

• Cat.No.: NTN1-0575H
• Product Overview: Recombinant Human NTN1 protein(Val22-Ala604), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with NaCl. Normally trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human Netrin-1, His Tag at 5 μg/mL (100 μL/well) can bind Human Netrin receptor DCC, Fc Tag with a linear range of 1-10 ng/mL.
• Molecular Mass: This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 67.5 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Proteinlength: Val22-Ala604
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Protein length: Val22-Ala604

Gene Information

• Gene Name: NTN1 netrin 1 [ Homo sapiens ]
• Official Symbol: NTN1
• Synonyms: NTN1; netrin 1; netrin-1; Netrin 1; NTN1L; netrin 1, mouse, homolog of
• Gene ID: 9423
• mRNA Refseq: NM_004822
• Protein Refseq: NP_004813
• MIM: 601614
• UniProt ID: O95631

Reviews

04/26/2022

It has high biological activity, high clearance rate and high safety.

02/03/2021

The storage conditions are broad and do not affect the activity of the protein,

01/27/2019

This protein is very reproducible.

Q&As

Are there have any use of NTN1 protein in cancer immunotherapy?

The targeted effect of NTN1 protein can be used to develop tumor immunotherapy drugs for the immune recognition and killing mechanism of tumors.

What are the applications of NTN1 protein in restorative and regenerative medicine?

NTN1 protein can help with cell migration, proliferation, and directed growth, so it may be a potential therapeutic target for cell therapy and restorative medicine.

In which diseases does NTN1 protein play an important role?

NTN1 protein not only plays an important role in the development of the nervous system, but also closely related to the occurrence and development of various diseases such as nervous system tumors, cardiovascular diseases and inflammatory diseases.

Is the NTN1 protein associated with inflammation?

Yes, NTN1 protein is involved in the regulatory process of inflammatory response and may play an important role in the occurrence and development of inflammatory diseases.

What is the role of NTN1 protein in autoimmune diseases?

This protein is closely related to the occurrence and progression of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, and may be involved in the regulation of autoimmune responses.

Why does NTN1 protein play a role in transplantation immunity?

NTN1 protein may be involved in the regulation of graft rejection, affecting immune tolerance and treatment efficacy after transplantation. It is also a potential transplant immunotherapy target.