Recombinant Rat Ntn1 protein, His/GST-tagged

Cat.No. : Ntn1-257R
Product Overview : Recombinant Rat Ntn1(Pro313~Pro565) fused with two N-terminal Tags, His-tag and GST-tag was expressed in E. coli.
Availability July 16, 2024
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Description : Ntn1 played an important role in many functions.
Source : E. coli
Species : Rat
Tag : His/GST
Form : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Molecular Mass : 60.5kDa
Protein length : Pro313~Pro565
AA Sequence : PECDRCKP FHYDRPWQRA TAREANECVA CNCNLHARRC RFNMELYKLS GRKSGGVCLN CRHNTAGRHC HYCKEGFYRD MGKPITHRKA CKACDCHPVG AAGKTCNQTT GQCPCKDGVT GITCNRCAKG YQQSRSPIAP CIKIPVAPPT TAASSMEEPE DCDSYCKASK GKLKMNMKKY CRKDYAVQIH ILKADKAGDW WKFTVNIISV YKQGTSRIRR GDQSLWIRSR DIAXKCPKIK PLKKYLLLGN AEDSP
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 90%
Applications : SDS-PAGE; WB; ELISA; IP.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Publication :
Netrin-1 Improves Functional Recovery through Autophagy Regulation by Activating the AMPK/mTOR Signaling Pathway in Rats with Spinal Cord Injury (2017)
Neuroprotection of netrin-1 on neurological recovery via Wnt/β-catenin signaling pathway after spinal cord injury (2020)
The Role of Netrin-1 in Improving Functional Recovery through Autophagy Stimulation Following Spinal Cord Injury in Rats (2017)
Gene Name : Ntn1 netrin 1 [ Rattus norvegicus ]
Official Symbol : Ntn1
Synonyms : NTN1; netrin 1; netrin-1;
Gene ID : 114523
mRNA Refseq : NM_053731
Protein Refseq : NP_446183
Chromosome Location : 10q24
Pathway : Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; DCC mediated attractive signaling, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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04/26/2022

    It has high biological activity, high clearance rate and high safety.

    02/03/2021

      The storage conditions are broad and do not affect the activity of the protein,

      01/27/2019

        This protein is very reproducible.

        Q&As (6)

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        Are there have any use of NTN1 protein in cancer immunotherapy? 09/24/2019

        The targeted effect of NTN1 protein can be used to develop tumor immunotherapy drugs for the immune recognition and killing mechanism of tumors.

        What are the applications of NTN1 protein in restorative and regenerative medicine? 07/21/2019

        NTN1 protein can help with cell migration, proliferation, and directed growth, so it may be a potential therapeutic target for cell therapy and restorative medicine.

        In which diseases does NTN1 protein play an important role? 07/13/2019

        NTN1 protein not only plays an important role in the development of the nervous system, but also closely related to the occurrence and development of various diseases such as nervous system tumors, cardiovascular diseases and inflammatory diseases.

        Is the NTN1 protein associated with inflammation? 06/10/2019

        Yes, NTN1 protein is involved in the regulatory process of inflammatory response and may play an important role in the occurrence and development of inflammatory diseases.

        What is the role of NTN1 protein in autoimmune diseases? 05/24/2019

        This protein is closely related to the occurrence and progression of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, and may be involved in the regulation of autoimmune responses.

        Why does NTN1 protein play a role in transplantation immunity? 02/11/2019

        NTN1 protein may be involved in the regulation of graft rejection, affecting immune tolerance and treatment efficacy after transplantation. It is also a potential transplant immunotherapy target.

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