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Active Recombinant Human UBE2C Protein, His-tagged

Cat.No. : UBE2C-643H
Product Overview : Recombinant Human UBE2C fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : UBE2C or ubiquitin-conjugating enzyme E2C is a member of the E2 ubiquitin-conjugating enzyme family which is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C acted as a dominant-negative inhibitor which blocks the destruction of mitotic cyclins A and B and the onset of anaphase in frog embryos and mammalian cells. High UBE2C mRNA expression is associated with poor disease-free survival and overall survival. High tumor grade, as well as high Ki67 protein expression, was more frequent in the high-expression group of UBE2C.
Source : E. coli
Species : Human
Tag : His
Form : 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Bio-activity : 16 nmol/min/mg
Molecular Mass : 21 kDa
Purity : >95%
Applications : Ubiquitin Enzyme Assay, Western Blot
Stability : 1 year at - 70 centigrade from the date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/ml
Gene Name : UBE2C ubiquitin-conjugating enzyme E2C [ Homo sapiens ]
Official Symbol : UBE2C
Synonyms : UBE2C; ubiquitin-conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; UBCH10; ubiquitin-protein ligase C; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme; dJ447F3.2;
Gene ID : 11065
mRNA Refseq : NM_007019
Protein Refseq : NP_008950
MIM : 605574
UniProt ID : O00762

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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