Active Recombinant Mouse Gzmb Protein (227 aa)
Cat.No. : | Gzmb-273G |
Product Overview : | Recombinant Mouse Granzyme B produced in CHO cells is a polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmGranzyme B has a molecular mass of 32 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Granzyme B is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.Granzyme B has also recently been found to be produced by a wide range of non-cytotoxic cells ranging from basophils and mast cells to smooth muscle cells. The secondary functions of granzyme B are also numerous. Granzyme B has been shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodeling. |
Source : | CHO |
Species : | Mouse |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | Measured by its ability to cleave a chromogenic peptide substrate (Ac-IEPD-pNA), the specific activity is greater than 1000 nM/min per μg of enzyme. |
Molecular Mass : | 32 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 227 |
AA Sequence : | IIGGHEVKPHSRPYMALLSIKDQQP EAICGGFLIREDFVLTAAHCEGSII NVTLGAHNIKEQEKTQQVIPMVKCI PHPDYNPKTFSNDIMLLKLKSKAKR TRAVRPLNLPRRNVNVKPGDVCYVA GWGRMAPMGKYSNTLQEVELTVQKD RECESYFKNRYNKTNQICAGDPKTK RASFRGDSGGPLVCKKVAAGIVSYG YKDGSPPRAFTKVSSFLSWIKKTMK SS |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant Mouse Granzyme B remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, recombinant Mouse Granzyme B should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | Gzmb granzyme B [ Mus musculus ] |
Official Symbol : | Gzmb |
Synonyms : | GZMB; granzyme B; granzyme B(G,H); fragmentin-2; cytotoxic cell protease 1; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1/C11; |
Gene ID : | 14939 |
mRNA Refseq : | NM_013542 |
Protein Refseq : | NP_038570 |
UniProt ID : | P04187 |
Products Types
◆ Recombinant Protein | ||
GZMB-3093H | Recombinant Human GZMB Protein, His (Fc)-Avi-tagged | +Inquiry |
Gzmb-4025M | Recombinant Mouse Gzmb Protein, His (Fc)-Avi-tagged | +Inquiry |
GZMB-33H | Active Recombinant Human GZMB Protein (19-247aa), C-His tagged | +Inquiry |
Gzmb-070M | Active Recombinant Mouse Gzmb Protein | +Inquiry |
Gzmb-2516M | Recombinant Mouse Gzmb Protein | +Inquiry |
◆ Lysates | ||
GZMB-2944HCL | Recombinant Human GZMB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0403 | GZMB Activity Fluorometric Assay Kit | +Inquiry |
Kit-0404 | GZMB Assay/Inhibitor Screening Fluorometric Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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