AP1 Reporter Kit (JNK Pathway)
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
|Product Overview :||The stress-activated protein kinase/c-jun N-terminal kinase (SAPK/JNK) family of proteins includes mitogen-activated protein kinases (MAPKs) that are activated by stress, inflammatory cytokines, mitogens, oncogenes, and inducers of cell differentiation and morphogenesis. Upon activation of the SAPK/JNK pathway, MAP Kinase Kinases phosphorylate and activate JNKs. The activated JNKs translocate to the nucleus where they phosphorylate and activate transcription factors such as c-Jun. The activated c-Jun forms homodimers or heterodimers with fos family proteins which bind to the activator protein-1(AP1) response element and induce target gene transcription.|
|Size :||500 reactions|
|Applications :||Monitor cAMP/PKA signaling pathway activity. Screen for activators or inhibitors of PKA or cAMP/PKA pathway components. Study effects of RNAi or gene overexpression on the activity of the cAMP/PKA pathway.|
|Storage :||Stable at least 12 months from date of receipt, when stored as directed (-20°C)|