AP1 Reporter Kit (JNK Pathway)

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AP1 Reporter Kit (JNK Pathway)

JNK Related Products

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Cat.No. : Kit-1679
Product Overview : The stress-activated protein kinase/c-jun N-terminal kinase (SAPK/JNK) family of proteins includes mitogen-activated protein kinases (MAPKs) that are activated by stress, inflammatory cytokines, mitogens, oncogenes, and inducers of cell differentiation and morphogenesis. Upon activation of the SAPK/JNK pathway, MAP Kinase Kinases phosphorylate and activate JNKs. The activated JNKs translocate to the nucleus where they phosphorylate and activate transcription factors such as c-Jun. The activated c-Jun forms homodimers or heterodimers with fos family proteins which bind to the activator protein-1(AP1) response element and induce target gene transcription.
Size : 500 reactions
Applications : Monitor cAMP/PKA signaling pathway activity. Screen for activators or inhibitors of PKA or cAMP/PKA pathway components. Study effects of RNAi or gene overexpression on the activity of the cAMP/PKA pathway.
Storage : Stable at least 12 months from date of receipt, when stored as directed (-20°C)
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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