Chloride intracellular channel 4

Cat.No. : CBCRY20
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  • Gene Information
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Cat. No. : CBCRY20
Background : Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Protein Classification : Transport protein
Structure Weight : 89641.50 Da
Polymer : 1
Molecule : Chloride intracellular channel protein 4
Chain Length : 261 amino acids
MMDB ID : 39169
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.8Å
Reference : Li, Y.F., Li, D.F., Zeng, Z.H., Wang, D.C. (2006) Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals Biochem.Biophys.Res.Commun. 343: 1272-1278
Gene Name : CLIC4
Synonyms : CLIC4L; DKFZp566G223; FLJ38640; H1; MTCLIC; huH1; p64H1; OTTHUMP00000003380; chloride intracellular channel 4 like; Intracellular chloride ion channel protein p64H1
UniProt ID : Q9Y696
Gene ID : 25932
Chromosome Location : 1p36.11
Function : chloride ion binding; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity.

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