Recombinant Human DNAJC19, His-tagged

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Recombinant Human DNAJC19, His-tagged

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Cat. No. : DNAJC19-3405H
Product Overview : Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA).
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Molecular Weight : 15.1 kDa (135aa) confirmed by MALDI-TOF.
Purity : > 90 % by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGRY VLQAMKHMEP QVKQVFQSLP KSAFSGGYYR GGFEPKMTKR EAALILGVSP TANKGKIRDA HRR IMLLNHP DKGGSPYIAA KINEAKDLLE GQAKK.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 [ Homo sapiens ]
Synonyms : DnaJ (Hsp40) homolog, subfamily C, member 19; Pam18; TIM14; TIMM14; DNAJC19;mitochondrial import inner membrane translocase subunit TIM14; OTTHUMP00000212660; homolog of yeast TIM14; OTTHUMP00000212661; OTTHUMP00000212662; Tim14; DnaJ homolog subfamily C member 19; OTTHUMP00000212663
Gene ID : 131118
mRNA Refseq : NM_001190233
Protein Refseq : NP_001177162
MIM : 608977
UniProt ID : Q96DA6
Chromosome Location : 3q26.33
Function : heat shock protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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