"DNAJC19" Related Products

Recombinant Human DNAJC19, His-tagged

Cat. No.: DNAJC19-3405H
Product Overview: Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA).
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Molecular Weight: 15.1 kDa (135aa) confirmed by MALDI-TOF.
Purity: > 90 % by SDS - PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGRY VLQAMKHMEP QVKQVFQSLP KSAFSGGYYR GGFEPKMTKR EAALILGVSP TANKGKIRDA HRR IMLLNHP DKGGSPYIAA KINEAKDLLE GQAKK.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 [ Homo sapiens ]
Synonyms: DnaJ (Hsp40) homolog, subfamily C, member 19; Pam18; TIM14; TIMM14; DNAJC19;mitochondrial import inner membrane translocase subunit TIM14; OTTHUMP00000212660; homolog of yeast TIM14; OTTHUMP00000212661; OTTHUMP00000212662; Tim14; DnaJ homolog subfamily C member 19; OTTHUMP00000212663
Gene ID: 131118
mRNA Refseq: NM_001190233
Protein Refseq: NP_001177162
MIM: 608977
UniProt ID: Q96DA6
Chromosome Location: 3q26.33
Function: heat shock protein binding

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