"PLK2" Related Products

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Recombinant Human Polo-like Kinase 2 (Drosophila), GST-tagged

Cat. No. : PLK2-565H
Product Overview : Recombinant Human full length Plk2 with N-terminal GST tag expressed in aBaculovirus infected Sf9 cellexpression system. MW =107 kDa.
Description : Serine/threonine-protein kinase PLK2 is an enzyme that in humans is encoded by the PLK2 gene. Serum-inducible kinase is a member of the "polo" family of serine/threonine protein kinases that have a role in normal cell division.
Source : Baculovirus infected Sf9 cell.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Purity : >80%.
Specific Activity : 4.6 pmol/min/μg enzyme reaction is conducted in a buffer containing 50mM HEPES (pH7.5), 10mM MgCl2, 1mM EGTA, 200μM ATP, 0.01% Brij-35 and 2μM substrate (SER/THR 16, Invitrogen) at room temperature for 1 hour.
Formulated In : 25mM Tris-HCl, pH 8.0, 100mM NaCl, 0.05% Tween-20, 50% glycerol, and 3mM DTT.
Stability : >6 months at -80°C.
Gene Name : PLK2 polo-like kinase 2 (Drosophila) [ Homo sapiens ]
Synonyms : polo-like kinase 2 (Drosophila); SNK; PLK2; serine/threonine-protein kinase PLK2; PLK-2; serum-inducible kinase; serine/threonine-protein kinase SNK;Serum-inducible kinase; polo-like kinase 2; Polo-like kinase 1; EC 2.7.11.21
Gene ID : 10769
mRNA Refseq : NM_006622.2
Protein Refseq : NP_006613.2
MIM : 607023
UniProt ID : Q9NYY3
Chromosome Location : 5q12.1-q13.2
Function : ATP binding; nucleotide binding; polo kinase kinase activity; protein binding; protein serine/threonine kinase activity; signal transducer activity; transferase activity

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