Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1 Serpine1-5282M

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Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1

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Cat. No. :	Serpine1-5282M
Product Overview :	Recombinant Mouse Serpine1was expressed in Mouse Plasma.
Description :	Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue.
Source :	Mouse Plasma
Species :	Mouse
Form :	Frozen Liquid
Specific Activity :	Undetectableconcentration of PAI1 Antigen.
Concentration :	< 0.1 ng/mLPAI1 Antigen
Storage :	Store at-70°C.
OfficialSymbol :	Serpine1
PAI-1 incomplex with the SMB domain of Vitronectin PDB 1OC0 :

Gene Name :	Serpine1 serine (or cysteine)peptidase inhibitor, clade E, member 1 [ Mus musculus ]
Synonyms :	Serpine1; serine (orcysteine) peptidase inhibitor, clade E, member 1; PAI1; PAI-1; Planh1;plasminogen activator inhibitor 1; PAI; serpin E1; plasminogen activatorinhibitor, type I; endothelial plasminogen activator inhibitor; nexin,plasminogen activator inhibitor type 1; serine (or cysteine) proteinaseinhibitor, clade E, member 1; Plasminogen activator inhibitor-1 precursor(PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
Gene ID :	18787
mRNA Refseq :	NM_008871
Protein Refseq :	NP_032897
UniProt ID :	P22777
Chromosome Location :	5 G2
Pathway :	Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Complement and coagulation cascades; Senescence andAutophagy; TGF Beta Signaling Pathway; p53 signaling pathway
Function :	protease binding;protein binding; serine-type endopeptidase inhibitor activity