"NGF" Related Products


Recombinant Human Nerve Growth Factor (beta polypeptide)

Cat. No. : NGF-1178H
Product Overview : Recombinant human NGFexpressed from human 293 cells as a non-disulfide bonded homodimeric proteinwith an apparent molecular mass of 13 kDa.
Description : NGF is critical forthe survival and maintenance of sympathetic and sensory nuerons and may playan important role in the regulation of the immune system . Nerve growthfactor (NGF) is a small secreted protein that is important for the growth,maintenance, and survival of certain target neurons (nerve cells). It alsofunctions as a signaling molecule.
Source : HEK 293 cells
Species : Human
MolecularWeight : 13 kDa,non-disulfide bonded homodimer, non-glycosylated.
Purity : >95%. The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
Endotoxin Level : Endotoxin Free
Biological Activity : 1 to 8 ng/mL ED50
OfficialSymbol : NGF
Rendering of NGFfrom PDB 1SG1. :

Gene Name : NGF nerve growth factor (betapolypeptide) [ Homo sapiens ]
Synonyms : NGF; nerve growthfactor (beta polypeptide); NGFB; HSAN5; Beta-NGF; MGC161426; MGC161428;beta-nerve growth factor; OTTHUMP00000013653; nerve growth factor, betasubunit
Gene ID : 4803
mRNA Refseq : NM_002506
Protein Refseq : NP_002497
MIM : 162030
UniProt ID : P01138
Chromosome Location : 1p13.1
Pathway : ARMS-mediatedactivation; Cell death signalling via NRAGE; Frs2-mediated activation; MAPKsignaling pathway; NADE modulates death signalling; NRAGE signals deaththrough JNK; PLC-gamma1 signalling; Retrograde neurotrophin signalling;Retrograde neurotrophin signalling; Signalling to p38 via RIT and RIN; TRKAactivation by NGF; p75NTR negatively regulates cell cycle via SC1; p75NTRregulates axonogenesis; p75NTR signals via NF-kB
Function : growth factoractivity; nerve growth factor receptor binding; receptor signaling proteinactivity; signal transducer activity

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