ngf
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  • Official Full Name
  • nerve growth factor (beta polypeptide)
  • Background
  • This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this genes expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
  • Synonyms
  • NGF; nerve growth factor (beta polypeptide); NGFB; HSAN5; Beta-NGF; beta-nerve growth factor; nerve growth factor, beta subunit;
Cat.#:NGF-814HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human NGF Protein, MYC/DDK-tagged
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Cat.#:Ngf-810MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ngf Protein
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Cat.#:NGF-495HTag:N/A
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human NGF
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Cat.#:NGF-573HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Nerve Growth Factor (beta polypeptide)
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Cat.#:NGF-1869HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Nerve Growth Factor (beta polypeptide)
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Cat.#:NGF-28HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Nerve Growth Factor (Beta Polypeptide)
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Cat.#:NGF-476HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Nerve Growth Factor (Beta Polypeptide)
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Cat.#:Ngf-354MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Nerve Growth Factor
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Cat.#:NGF-001HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF, HIgG1 Fc-tagged, mutant
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Cat.#:NGF-002HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF, MIgG2a Fc-tagged
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Cat.#:NGF-003HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF, HIgG1 Fc-tagged
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Cat.#:NGF-05HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF, None tagged
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Cat.#:NGF-11HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Pro-Nerve Growth Factor
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Cat.#:NGF-1287HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NGF, GST-tagged
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Cat.#:NGF-14HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Nerve Growth Factor (Beta Polypeptide)
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Cat.#:NGF-29561THTag:
Source (Host):Species:Human
Product nameRecombinant Human NGF
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Cat.#:NGF-29918THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NGF
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Cat.#:NGF-425HTag:His
Source (Host):HEK293FSpecies:Human
Product nameRecombinant Human NGF protein, His-tagged
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Cat.#:NGF-479HTag:
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human NGF
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Cat.#:NGF-537HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NGF protein, His-tagged
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Cat.#:NGF-54HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human NGF
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Cat.#:NGF-588HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human NGF protein
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Cat.#:Ngf-09MTag:N/A
Source (Host):Submaxillary gland of grown mouseSpecies:Mouse
Product nameMouse Nerve Growth Factor, Liquid
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Cat.#:Ngf-10MTag:N/A
Source (Host):Submaxillary gland of grown mouseSpecies:Mouse
Product nameMouse Nerve Growth Factor, Lyophilized
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Cat.#:Ngf-477MTag:N/A
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Ngf, None tagged
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Cat.#:Ngf-8330MTag:
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Ngf
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Cat.#:NGF-5531CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NGF
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Cat.#:NGF-9894ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NGF
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Cat.#:NGF-534HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF
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Cat.#:Ngf-662MTag:N/A
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Nerve Growth Factor
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Cat.#:NGF-1178HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Nerve Growth Factor (beta polypeptide)
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Cat.#:Ngf-182MTag:
Source (Host):Submaxillary Gland of Grown MouseSpecies:Mouse
Product nameNative Mouse Ngf Protein
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Cat.#:Ngf-298MTag:
Source (Host):Mouse Submaxillary GlandSpecies:Mouse
Product nameNative Mouse Nerve Growth Factor
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Cat.#:Ngf-51MTag:
Source (Host):Species:Mouse
Product nameNative Mouse Nerve Growth Factor 2.5S
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Cat.#:NGF-001HCLTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human NGF cell lysate
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Cat.#:NGF-001MCLTag:
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse NGF cell lysate
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Cat.#:NGF-128HTag:
Source (Host):Species:Human
Product nameHuman Nerve Growth Factor(rDNA derived) Reference standard
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Involved Pathway

Ngf involved in several pathways and played different roles in them. We selected most pathways Ngf participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ngf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MAP2K4; GADD45B; MEF2C; CACNA1D; ATF4B1; MKNK2A; MOS; PLA2G4AA; FGF14; PTPRR
Ras signaling pathway
GNGT1; PLA2G4F; IKBKB; PLA2G2D; RASGRF2; PLCG2; PIK3CD; FIGF; MAPK10; MAPK3
Rap signaling pathway
PDGFRB; BCAR1; MAPK12; MAPK13; NGFR; FYB; Pdgfa&Pdgfb; RALGDS; PIK3R1; FGF4
PIK-Akt signaling pathway
GRB2; NR4A1; VEGFA; AKT1; LPAR3; LAMA2; THBS1; YWHAG; TCL1B; PIK3CA
Apoptosis
MAP3K14; PRKACAA; HMGB2; Fasl; Casp3; HMGB2A; MYC; PPP3CCA; RELA; STK26
Neurotrophin signaling pathway
CALM1; YWHAE; AKT2; PRKCD; IRAK1; BDNF; RAP1A; MAP2K2; MAP2K5; PTPN11
Inflammatory mediator regulation of TRP channels
CALML3; PIK3CG; PLCG1; PIK3R1; ACCN4; PLCB4; PIK3R2; CYP2C37; PLA2G4D; TRPA1

Protein Function

Ngf has several biochemical functions, for example, growth factor activity, metalloendopeptidase inhibitor activity, nerve growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ngf itself. We selected most functions Ngf had, and list some proteins which have the same functions with Ngf. You can find most of the proteins on our site.
Function
Related Protein
Function growth factor activity
Related Protein MDKB; NRG1; PDGFAA; THPO; GDNFA; KITLG; PDGFD; BMP15; TGFB3; FGF20B
Function metalloendopeptidase inhibitor activity
Related Protein BST2; WFIKKN1; TIMP2; COL4A3; TIMP4; NGF; TIMP2A; WFIKKN2; TIMP1; LXN
Function nerve growth factor receptor binding
Related Protein NTF7; NGF
Function protein binding
Related Protein ZNF34; MARVELD3; C19orf80; DUT; CD244; TMX3; ODC1; FOXL2; SWSAP1; LARP2
Function receptor signaling protein activity
Related Protein RGS14; ARAF; FCGR1A; ADRB1; DAXX; IFITM1; NGF; FCAR; TIAM2; FLRT2

Interacting Protein

Ngf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ngf here. Most of them are supplied by our site. Hope this information will be useful for your research of Ngf.
NTRK1; Ngfr; NGFR; SORT1; SORCS3

Ngf Related Articles

Gezginci-Oktayoglu, S; Karatug, A; et al. Nerve Growth Factor Neutralization Suppresses beta-Cell Proliferation Through Activin A and Betacellulin. PANCREAS 44:243-249(2015).
Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).

Ngf Related Gene Family

Cytokines