ngf Protein, nerve growth factor (beta polypeptide)


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Official Full Name nerve growth factor (beta polypeptide)
Background This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this genes expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
Synonyms NGF; nerve growth factor (beta polypeptide); NGFB; HSAN5; Beta-NGF; beta-nerve growth factor; nerve growth factor, beta subunit;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293F
    • Human
    • Mammalian Cell
    • Mouse
    • Mouse Submaxillary Gland
    • NS0
    • NSO
    • Submaxillary gland
    • Submaxillary Gland of Grown Mouse
    • Yeast
    • Tag :
    • Fc
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NGF-589H Recombinant Human NGF(Arg 121 Gly) protein HEK293 N/A
    Human NGF-001H Recombinant Human NGF, HIgG1 Fc-tagged, mutant CHO Fc
    Human NGF-001HCL Recombinant Human NGF cell lysate CHO N/A
    Human NGF-002H Recombinant Human NGF, MIgG2a Fc-tagged CHO Fc
    Human NGF-003H Recombinant Human NGF, HIgG1 Fc-tagged CHO Fc
    Human NGF-05H Recombinant Human NGF, None tagged CHO N/A
    Human NGF-1178H Recombinant Human Nerve Growth Factor (beta polypeptide) HEK293 N/A
    Human NGF-11H Recombinant Human Pro-Nerve Growth Factor E.coli N/A
    Human NGF-1287H Recombinant Human NGF, GST-tagged E.coli GST
    Human NGF-128H Human Nerve Growth Factor(rDNA derived) Reference standard N/A
    Human NGF-14H Recombinant Human Nerve Growth Factor (Beta Polypeptide) HEK293 N/A
    Human NGF-1869H Recombinant Human Nerve Growth Factor (beta polypeptide) E.coli N/A
    Human NGF-28H Recombinant Human Nerve Growth Factor (Beta Polypeptide) NSO N/A
    Human NGF-29561TH Recombinant Human NGF N/A
    Human NGF-29918TH Recombinant Human NGF E.coli N/A
    Human NGF-425H Recombinant Human NGF protein, His-tagged HEK293F His
    Human NGF-476H Recombinant Human Nerve Growth Factor (Beta Polypeptide) Mammalian Cell N/A
    Human NGF-479H Recombinant Human NGF NS0 N/A
    Human NGF-495H Recombinant Human NGF CHO N/A
    Human NGF-534H Recombinant Human NGF Human N/A
    Human NGF-537H Recombinant Human NGF protein, His-tagged E.coli His
    Human NGF-54H Recombinant Human NGF Yeast N/A
    Human NGF-573H Recombinant Human Nerve Growth Factor (beta polypeptide) E.coli N/A
    Human NGF-588H Recombinant Human NGF protein HEK293 N/A
    Human NGF-814H Recombinant Human NGF Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse NGF-001MCL Recombinant Mouse NGF cell lysate CHO N/A
    Mouse Ngf-09M Mouse Nerve Growth Factor, Liquid Submaxillary gland N/A
    Mouse Ngf-10M Mouse Nerve Growth Factor, Lyophilized Submaxillary gland N/A
    Mouse Ngf-182M Native Mouse Ngf Protein Submaxillary Gland of Grown Mouse N/A
    Mouse Ngf-298M Native Mouse Nerve Growth Factor Mouse Submaxillary Gland N/A
    Mouse Ngf-354M Recombinant Mouse Nerve Growth Factor NSO N/A
    Mouse Ngf-477M Recombinant Mouse Ngf, None tagged CHO N/A
    Mouse Ngf-51M Native Mouse Nerve Growth Factor 2.5S Mouse Submaxillary Gland N/A
    Mouse Ngf-662M Recombinant Mouse Nerve Growth Factor Mouse N/A
    Mouse Ngf-810M Recombinant Mouse Ngf Protein E.coli N/A
    Mouse Ngf-8330M Recombinant Mouse Ngf NS0 N/A
    Chicken NGF-5531C Recombinant Chicken NGF Mammalian Cell His
    Zebrafish NGF-9894Z Recombinant Zebrafish NGF Mammalian Cell His

    ngf involved in several pathways and played different roles in them. We selected most pathways ngf participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ngf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway ABL1; FGF12; RAP1B; Pdgfa&Pdgfb; PIK3R5; SHOC2; RAC3; VEGFC; FOXO4; RALGDS
    Rap signaling pathway HRAS; MAPK11; MLLT4; CALML3; FGF8; CALM3; PFN3; GNAI2; ANGPT1; FGF10
    PIK-Akt signaling pathway FGF13; GNG12; Il6ra; ITGB3; PPP2R5E; PPP2R3A; PDGFB; VWF; NR4A1; PDPK1
    Apoptosis PTBP3; PRKAR2B; TRP53; DAPK1; HRK; CAPN1B; CAPN2L; JUN; PIK3R2; IRF6
    Neurotrophin signaling pathway MAP2K5; CAMK2A; PIK3R5; NTRK3; CALM4; RPS6KA3; PIK3CA; TP73; CALML3; NTF3
    Inflammatory mediator regulation of TRP channels IL1B; IL1RAP; TRPA1; PIK3CD; BDKRB1; ITPR3; CYP2C38; PPP1CB; CYP2J5; GNAQ

    ngf has several biochemical functions, for example, growth factor activity, metalloendopeptidase inhibitor activity, nerve growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ngf itself. We selected most functions ngf had, and list some proteins which have the same functions with ngf. You can find most of the proteins on our site.

    Function Related Protein
    growth factor activity GRN; IL6; FGF11; FGF1; FGF5; SPAW; TGFB1; GDNF; FGF20A; NRTN
    metalloendopeptidase inhibitor activity WFIKKN1; FETUB; TIMP3; SPOCK1; WFIKKN2; TIMP2; BST2; NGF; RECK; TIMP2A
    nerve growth factor receptor binding NGF; NTF7
    protein binding MMRN2; CRYAB; GLRA1; IFI16; APOH; ADAM12; POU2F1; ZKSCAN4; NRG4; LRPPRC
    receptor signaling protein activity FLRT3; BAG1; KLK1B4; GNAZ; FCGR1A; RGS14; RGS12B; KLK1B3; PLCG1; SMAD1

    ngf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ngf here. Most of them are supplied by our site. Hope this information will be useful for your research of ngf.

    NTRK1; Ngfr; NGFR; SORT1; SORCS3

    Gezginci-Oktayoglu, S; Karatug, A; et al. Nerve Growth Factor Neutralization Suppresses beta-Cell Proliferation Through Activin A and Betacellulin. PANCREAS 44:243-249(2015).
    Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).

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