"FGF2" Related Products

Recombinant Bovine Fibroblast Growth Factor 2

Cat. No.: FGF2-650B
Product Overview: Recombinantbovine FGF2 is a single, non-glycosylated polypeptide chain containing 172amino acids.
Description: FGF2 is a single-chainpolypeptide growth factor that plays a significant role in the process ofwound healing and is a potent inducer of angiogenesis. Several different formsof the human protein exist ranging from 18-24 kDa in size due to the use of alternativestart sites within the FGF2 gene.
Source: Bovine
Host: E. coli
Form: Lyophilized from asterile filtered solution in PBS, pH 7.4 + 4% mannitol.
Purity: >97% by SDS-PAGEand HPLC analyses.
Sequence: MTMITNSSSVPGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLY CKNGGFFLRI HPDGRVDGVR EKSDPHIKLQLQAEERGVVS IKGVCANRYL AMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQY KLGPKTGPGQKAILFLPMSA KS
Molecular Weight: 18.5 kDa
Biological Activity: Calculated by the dose dependantproliferation of BALB/c 3T3 cells, the ED50 is < 1.0 ng/ml.
Endotoxin: <1 ng/μg of FGF2
Reconstitution: Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be madein appropriate buffered solutions.
Storage: Stable at2-8°C, but best kept desiccated -20°C. Upon reconstitution, stable for up to1 week at 2-8°C. For longer term, store in working aliquots below -20°C.Avoid repeated freeze/thaw cycles.
OfficialSymbol: FGF2
Pathways: MAPKsignaling pathway; Melanoma; Pathways in cancer; Regulation of actincytoskeleton
Gene Name: FGF2 fibroblastgrowth factor 2 (basic) [ Bos taurus ]
Synonyms: FGF2; fibroblast growthfactor 2 (basic); heparin-binding growth factor 2; BFGF; HBGF-2;basic fibroblast growth factor; Heparin-binding growth factor 2; Basicfibroblast growth factor; bFGF; FGF-2
Gene ID: 281161
mRNA Refseq: NM_174056
Protein Refseq: NP_776481
UniProt ID: P03969
Chromosome Location: 17
Function: growth factor activity; heparinbinding; protein binding; voltage-gated calcium channel activity

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