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Recombinant Bovine Fibroblast Growth Factor 2

Cat.No. : FGF2-650B
Product Overview : Recombinantbovine FGF2 is a single, non-glycosylated polypeptide chain containing 172amino acids.
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  • Gene Information
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Cat. No. : FGF2-650B
Description : FGF2 is a single-chainpolypeptide growth factor that plays a significant role in the process ofwound healing and is a potent inducer of angiogenesis. Several different formsof the human protein exist ranging from 18-24 kDa in size due to the use of alternativestart sites within the FGF2 gene.
Source : Bovine
Host : E. coli
Form : Lyophilized from asterile filtered solution in PBS, pH 7.4 + 4% mannitol.
Purity : >97% by SDS-PAGEand HPLC analyses.
Sequence : MTMITNSSSVPGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLY CKNGGFFLRI HPDGRVDGVR EKSDPHIKLQLQAEERGVVS IKGVCANRYL AMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQY KLGPKTGPGQKAILFLPMSA KS
Molecular Weight : 18.5 kDa
Biological Activity : Calculated by the dose dependantproliferation of BALB/c 3T3 cells, the ED50 is < 1.0 ng/ml.
Endotoxin : <1 ng/μg of FGF2
Reconstitution : Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be madein appropriate buffered solutions.
Storage : Stable at2-8°C, but best kept desiccated -20°C. Upon reconstitution, stable for up to1 week at 2-8°C. For longer term, store in working aliquots below -20°C.Avoid repeated freeze/thaw cycles.
OfficialSymbol : FGF2
Pathways : MAPKsignaling pathway; Melanoma; Pathways in cancer; Regulation of actincytoskeleton
Gene Name : FGF2 fibroblastgrowth factor 2 (basic) [ Bos taurus ]
Synonyms : FGF2; fibroblast growthfactor 2 (basic); heparin-binding growth factor 2; BFGF; HBGF-2;basic fibroblast growth factor; Heparin-binding growth factor 2; Basicfibroblast growth factor; bFGF; FGF-2
Gene ID : 281161
mRNA Refseq : NM_174056
Protein Refseq : NP_776481
UniProt ID : P03969
Chromosome Location : 17
Function : growth factor activity; heparinbinding; protein binding; voltage-gated calcium channel activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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