Recombinant Human Anaphase Promoting Complex Subunit 13, T7-tagged

• Cat.No.: ANAPC13-1919H
• Product Overview: Recombinant humanANAPC13 protein fused to T7-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Species: Human
• Tag: T7
• Description: ANAPC13,also known as anaphase-promoting complex subunit 13, is component of theanaphase promoting complex, a large ubiquitin-protein ligase that controlscell cycle progression by regulating the degradation of cell cycle regulatorssuch as B-type cyclins.
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl.
• Molecular Weight: 10.0 kDa(89aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appearhigher)
• Purity: > 90%by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MASMTGGQQMGRGSHMDSEV QRDGRILDLI DDAWREDKLP YEDVAIPLNE LPEPEQDNGG TTESVKEQEM KWTDLALQYLHENVPPIGN
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: FOXA2 and FOXA3 transcription factornetworks; Fructose and mannose metabolism; Fructose catabolism;Gluconeogenesis; Glucose metabolism; Glycolysis; Glycolysis (Embden-Meyerhofpathway); Glycolysis / Gluconeogenesis; Glycolysis and Gluconeogenesis;Metabolic pathways; Metabolism of carbohydrates; Pentose phosphate pathway

Gene Information

• Gene Name: ANAPC13 anaphase promotingcomplex subunit 13 [ Homo sapiens ]
• Official Symbol: ANAPC13
• Synonyms: ANAPC13; anaphase promoting complex subunit13; SWM1; APC13; anaphase-promoting complex subunit 13; cyclosome subunit 13;DKFZP566D193
• Gene ID: 25847
• mRNA Refseq: NM_001242374
• Protein Refseq: NP_001229303
• UniProt ID: Q9BS18
• Chromosome Location: 3q22.1
• Function: APC/C complex; Adaptive Immune System; Cellcycle; Class I MHC mediated antigen processing snd presentation; ImmuneSystem; Oocyte meiosis; Progesterone-mediated oocyte maturation; Ubiquitinmediated proteolysis