"LRRTM1" Related Products

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Recombinant Human Leucine Rich Repeat Transmembrane Neuronal 1, His-tagged

Cat. No.: LRRTM1-5682H
Product Overview: Recombinant Human LRRTM1protein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Ala35-Ile425.
Description: Human LRRTM1 is a58-59 kDa type I transmembrane protein that belongs to the LRRTM family ofproteins within the leucine-rich repeat superfamily. It is synthesized as aprecursor with a 34 amino acid signal sequence, a 393 aa luminal region, a 21aa transmembrane region, and a 74 aa cytoplasmic region. The luminal portionof LRRTM1 contains three N-linked glycosylation sites and 10 LRRs flanked bycysteine-rich domains. The cytoplasmic region contains several tyrosine,serine, and threonine residues that have potential to be phosphorylated andthus to be involved in signal transduction.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence: Ala35
Molecular Weight: 44.4 kDa
Activity: Measuredby its ability to enhance neurite outgrowth of E18 rat embryonic corticalneurons. Able to significantly enhance neurite outgrowth when immobilized at6-25 μg/mL on a nitrocellulose-coated microplate.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE: 70-85kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: 100μg/mL in sterile PBS
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
Gene Name: LRRTM1 leucine rich repeattransmembrane neuronal 1 [ Homo sapiens ]
Official Symbol: LRRTM1
Synonyms: LRRTM1; leucine richrepeat transmembrane neuronal 1; FLJ32082; leucine-rich repeat transmembraneneuronal protein 1; leucine-rich repeat transmembrane neuronal 1 protein;UNQ675/PRO1309; OTTHUMP00000194829; OTTHUMP00000202801; OTTHUMP00000203404
Gene ID: 347730
mRNA Refseq: NM_178839
Protein Refseq: NP_849161
MIM: 610867
UniProt ID: Q86UE6
Chromosome Location: 2p12
Function: molecular function

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