Active Recombinant Human Laminin α4
Cat.No. : | LAMA4-6952H |
Product Overview : | Recombinant Human Lamininα4 protein, was expressed in Chinese Hamster Ovary cell line, CHOderived andpurified by SDS-PAGE |
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- Gene Information
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Cat. No. : | LAMA4-6952H |
Description : | Laminin subunitalpha-4 is a protein that in humans is encoded by the LAMA4 gene. Laminins, afamily of extracellular matrix glycoproteins, are the major noncollagenousconstituent of basement membranes. They have been implicated in a widevariety of biological processes including cell adhesion, differentiation,migration, signaling, neurite outgrowth and metastasis. Laminins are composedof 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, andB2, respectively) and they form a cruciform structure consisting of 3 short arms,each formed by a different chain, and a long arm composed of all 3 chains.Each laminin chain is a multidomain protein encoded by a distinct gene.Several isoforms of each chain have been described |
Source : | CHO Cells |
MolecularMass : | 111 kDa |
Purity : | >90%, by SDSPAGE underreducing conditions and visualized by silver stain. |
Activity : | Measured by theability of the immobilized protein to support the adhesion of HT1080 humanfibrosarcoma cells. The ED50 for this effect is typically 0.7-2.8 μg/mL.Optimal dilutions should be determined by each laboratory for eachapplication |
EndotoxinLevel : | <1.0 EU per 1 μgof the protein by the LAL method. |
N-terminalSequenceAnalysis : | Gln826 predicted,sequencing might be blocked, no result obtained |
Formulation : | Lyophilized from a0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 200μg/mL in PBS |
Storage : | Use a manual defrostfreezer and avoid repeated freeze thaw Cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution. |
Gene Name : | LAMA4 laminin, alpha 4 [ Homosapiens ] |
Official Symbol : | LAMA4 |
Synonyms : | LAMA4;laminin, alpha 4; LAMA3; LAMA4*-1; DKFZp686D23145; Laminin-14 subunit alpha;Laminin-8 subunit alpha; Laminin-9 subunit alpha |
Gene ID : | 3910 |
mRNA Refseq : | NM_001105206 |
Protein Refseq : | NP_001098676 |
MIM : | 600133 |
UniProt ID : | Q16363 |
Chromosome Location : | 6q21 |
Pathway : | extracellularmatrix structural constituent; receptor binding |
Function : | Africantrypanosomiasis; Amoebiasis; ECM-receptor interaction; FOXM1 transcriptionfactor networ; Focal adhesion; Pathways in cancer; Small cell lung cancer;Toxoplasmosis |
Products Types
◆ Recombinant Protein | ||
LAMA4-4980M | Recombinant Mouse LAMA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Lama4-214M | Recombinant Mouse Lama4 Protein, His-tagged | +Inquiry |
LAMA4-213H | Recombinant Human LAMA4 Protein, His-tagged | +Inquiry |
LAMA4-6953H | Recombinant Human Laminin α4, GST-tagged | +Inquiry |
LAMA4-6954M | Active Recombinant Mouse Laminin α4, His-tagged | +Inquiry |
◆ Lysates | ||
LAMA4-967HCL | Recombinant Human LAMA4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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