|Product Overview:||Recombinant Human CD-105 protein 26-176 a.a. expressed in E.coli,43 kDa.|
|Description:||CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGFBeta1 and Beta3 with high affinity but not TGF-Beta2.|
|Synonyms:||ENG; CD105; END; FLJ41744; HHT1; ORW; ORW1; endoglin; CD105 antigen; OTTHUMP00000022221; Osler-Rendu-Weber syndrome 1.|
|Presentation:||Recombinant Human CD-105 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.|
|Applications:||•ELISA•Inhibition Assays •Western Blotting|
|Characterization:||On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.|
|Storage:||Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.|
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