Recombinant Human PFDN5 protein, His-tagged
Cat.No. : | PFDN5-3608H |
Product Overview : | Recombinant Human PFDN5(1-154aa) fused with His tag at N-terminal was expressed in E. coli. |
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Description : | PFDN5 belongs to the prefoldin alpha subunit family. Prefoldin (PFDN), a ubiquitously expressed heterohexameric co-chaperone, is necessary for proper folding of nascent proteins, in particular, tubulin and actin. PFDN5 is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. This protein may also repress the transcriptional activity of the proto-oncogene c-Myc. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol |
Molecular Mass : | 19.5kDa (174aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSHYVPGKLHDVE HVLIDVGTGY YVEKTAEDAK DFFKRKIDFL TKQMEKIQPA LQEKHAMKQA VMEMMSQKIQ QLTALGAAQA TAKAMAQSINITEL NLPQLEMLKN QLDQEVEFLS TSIAQLKVVQ TKYVEAKDCL NVLNKSNEGK ELLVPLTSSM |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Publication : |
Prefoldin 5 and anti-prefoldin 5 antibodies as biomarkers for uveitis in ankylosing spondylitis (2019)
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Gene Name : | PFDN5 prefoldin subunit 5 [ Homo sapiens ] |
Official Symbol : | PFDN5 |
Synonyms : | PFDN5; prefoldin subunit 5; prefoldin 5; MM 1; PFD5; myc modulator-1; c-myc binding protein; MM1; MM-1; MGC5329; MGC71907; |
Gene ID : | 5204 |
mRNA Refseq : | NM_002624 |
Protein Refseq : | NP_002615 |
MIM : | 604899 |
UniProt ID : | Q99471 |
Chromosome Location : | 12q13.13 |
Pathway : | Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem; |
Function : | protein binding; transcription corepressor activity; unfolded protein binding; |
Products Types
◆ Recombinant Protein | ||
PFDN5-6652M | Recombinant Mouse PFDN5 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFDN5-6432H | Recombinant Human PFDN5 Protein(2-154aa), GST-tagged | +Inquiry |
PFDN5-3200R | Recombinant Rhesus Macaque PFDN5 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFDN5-2580H | Recombinant Human PFDN5 Protein, His-tagged | +Inquiry |
PFDN5-12661M | Recombinant Mouse PFDN5 Protein | +Inquiry |
◆ Lysates | ||
PFDN5-3278HCL | Recombinant Human PFDN5 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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