Active Recombinant Mouse Fgfr1 protein(Met1-Glu376), hFc-tagged
Cat.No. : | Fgfr1-4015M |
Product Overview : | Recombinant Mouse FGFR1 isoform 1 (P16092-1)(Met 1-Glu 376) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | C-hFc |
Protein length : | Met1-Glu376 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to inhibit mouse FGF acidic (aFGF/FGF1) dependent prolifeRation of Balb/C 3T3 mouse fibroblasts. The ED50 for this effect is typically 6-25 ng/mL in the presence of 0.5 ng/mL of mouse FGF acidic (aFGF/FGF1). |
Molecular Mass : | The secreted recombinant mouse FGFR1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 596 amino acids and has a calculated molecular mass of 66.5 kDa. The apparent molecular mass of rmFGFR1/Fc monomer is approximately 100-110 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Fgfr1 fibroblast growth factor receptor 1 [ Mus musculus ] |
Official Symbol : | Fgfr1 |
Synonyms : | FGFR1; fibroblast growth factor receptor 1; MFR; c-fgr; bFGF-R-1; proto-oncogene c-Fgr; basic fibroblast growth factor receptor 1; FLG; Eask; Hspy; Flt-2; Fgfr-1; AW208770; |
Gene ID : | 14182 |
mRNA Refseq : | NM_001079908 |
Protein Refseq : | NP_001073377 |
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◆ Lysates | ||
FGFR1-2765HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
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◆ Assay kits | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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