Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged
Cat.No. : | FGFR1-316H |
Product Overview : | rh FGFR1 contains C terminal 6 His Tag and has a calculated MW of 42.5 kDa. In DTT-reduced SDS-PAGE, protein migrates as 60 - 65 kDa. |
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Cat. No. : | FGFR1-316H |
Description : | Fibroblast growth factor receptor 1 (FGFR1) is also known as basic fibroblast growth factor receptor 1(BFGFR1), FMS-like tyrosine kinase, CD331, and is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. This protein is one of several fibroblast growth factor receptors, which are related proteins that are involved in important processes such as cell division regulation of cell growth and maturation formation of blood vessels involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and embryonic development. |
Source : | Recombinant human FGFR1 (rh FGFR1) Met1- Ile376 (Accession AAH18128) fused with C terminal 6 His Tag was expressed in human 293 cells (HEK293). |
Species : | Human |
Form : | Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder Normally 5-8% trehalose and mannitol are powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization. |
Purity : | >95% purity as determined by SDS-PAGE of reduced rh FGFR1. |
Endotoxin : | Less than 0.01 ng endotoxin per μg rh FGFR1. |
Storage : | Stable in lyophilized state at 4°C for 1 year after receipt. Sterile stock solutions reconstituted are stable at 4°C for 2 months and at -20°C for 6 months. Avoid repeated freeze-thaw cycles. |
Publication : |
FGFR1 mediates recombinant thrombomodulin domain-induced angiogenesis. (2015)
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Gene Name : | FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ] |
Official Symbol : | FGFR1 |
Synonyms : | FGFR1; fibroblast growth factor receptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; FGFR-1; HBGFR; N-SAM; FLJ99988; bFGF-R-1; soluble FGFR1 variant 1; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1; EC 2.7.10.1; OTTHUMP00000190881; OTTHUMP00000190885; OTTHUMP00000190874; OTTHUMP00000190875; OTTHUMP00000190876; OTTHUMP00000190877; OTTHUMP00000190879; OTTHUMP00000190880 |
Gene ID : | 2260 |
mRNA Refseq : | NM_015850 |
Protein Refseq : | NP_056934 |
MIM : | 136350 |
UniProt ID : | P11362 |
Chromosome Location : | 8p12 |
Pathway : | Adherens junction; MAPK signaling pathway; elanoma; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Axon guidance; Signaling by FGFR |
Function : | ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
FGFR1-2056H | Recombinant Human FGFR1 Protein, His-tagged | +Inquiry |
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Fgfr1-3000M | Recombinant Mouse Fgfr1 Protein, Myc/DDK-tagged | +Inquiry |
FGFR1-28H | Recombinant Active Human FGFR1 (W666R) Mutant Protein, GST-tagged | +Inquiry |
FGFR1-5C | Recombinant Cynomolgus Monkey FGFR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FGFR1-476HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
FGFR1-2133MCL | Recombinant Mouse FGFR1 cell lysate | +Inquiry |
FGFR1-2765HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1590 | FGFR1 Functional Assay Kit | +Inquiry |
Kit-1557 | U2OS FGFR1 Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDEFB103A plays a role in maintaining a balanced microbiome by exerting selective antimicrobial activity. Understanding this interaction is crucial for potential applications in microbiome-related disorders.
Research suggests that altered levels of DEFB103A expression may be associated with certain diseases. However, its specific use as a diagnostic marker requires further validation.
While research is ongoing, potential side effects and concerns related to the therapeutic use of DEFB103A or its analogs need to be thoroughly investigated, including any possible immunogenicity.
DEFB103A plays a crucial role in the innate immune system by acting as an antimicrobial peptide. It helps defend the body against a wide range of pathogens, including bacteria, viruses, and fungi.
DEFB103A deficiency has been linked to an increased susceptibility to various infections, particularly those affecting the skin and mucosal surfaces.
Customer Reviews (3)
Write a reviewFGFR1, a calcium-dependent phospholipid-binding protein, plays a crucial role in various cellular processes, making it a valuable tool for investigation.
When combined with the support and quality assurance provided by the manufacturer, researchers can confidently utilize FGFR1 protein to unravel the intricate mechanisms underlying cellular processes, ultimately advancing scientific knowledge.
The manufacturer can contribute to the research process by providing top-quality FGFR1 protein that meets rigorous standards of purity, stability, and reliability.
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