Active Recombinant Human IFNB1

• Cat.No.: IFNB1-99H
• Product Overview: Human IFNB1 (P01574, 22 a.a.-187 a.a.) partial recombinant protein expressed in CHO cells.

Specification

• Cat. No.: IFNB1-99H
• Description: Interferon beta is a protein that in humans is encoded by the IFNB1 gene.
• Sequence: MSYNLLGFL QRSSNFQCQK LLWQLNGRLE YCLKDRMNFD IPEEIKQLQQ FQKEDAALTI YEMLQNIFAI FRQDSSSTGW NETIVENLLA NVYHQINHLK TVLEEKLEKE DFTRGKLMSS LHLKRYYGRI LHYLKAKEYS HCAWTIVRVE ILRNFYFINR LTGYLRN
• Theoretical MW (kDa): 19
• Form: Lyophilized
• Preparation Method: Mammalian cell (CHO) expression system
• Purity: > 98% by SDS-PAGE and HPLC
• Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
• Activity: The activity was determined by the viral resistance assay of Human WISH cells was found to be in the range of 3 x 10⁸ IU/mg.
• Application: SDS-PAGE
• Storage Buffer: Lyophilized from sodium acetate solution pH 4.8
• Storage: Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
• Unitprot ID: P01574
• Pathways: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway

Gene Information

• Gene Name: IFNB1 interferon, beta 1, fibroblast [ Homo sapiens ]
• Official Symbol: IFNB1
• Synonyms: IFNB1; Interferon, beta 1, fibroblast; IFB; IFF; IFNB; MGC96956; Interferon beta; Leukocyte interferon; B cell interferon; Type I interferon; IFNB1; IFN-b 1a; IFN-beta; OTTHUMP00000021131; Fibroblast interferon
• Gene ID: 3456
• mRNA Refseq: NM_002176
• Protein Refseq: NP_002167
• MIM: 147640
• Chromosome Location: 9p21
• Function: cytokine activity; interferon-alpha/beta receptor binding; transcription corepressor activity