"KAT8" Related Products


Recombinant Human K(Lysine) Acetyltransferase 8, GST-tagged

Cat. No.: KAT8-1602H
Product Overview: Recombinant human KAT8 (2-467; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: KAT8 (MYST1) or MYST histone acetyltransferase 1 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. MYST1 have a chromodomain that involved in protein-protein interactions and targeting transcriptional regulators to chromatin. MYST histone acetyltransferase 1 is also involved in ATM function.
Applications: Western Blot
Molecular Weight: 83 kDa
Expression System: Sf9 insect cells using baculovirus.
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: > 80 %
Concentration: 0.1 ug/ul
Sequences: 2-467
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: p53 pathway
Gene Name: KAT8 K(lysine) acetyltransferase 8 [ Homo sapiens ]
Official Symbol: KAT8
Synonyms: KAT8; MOF; hMOF; MYST1; FLJ14040; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; EC; histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1
Gene ID: 84148
mRNA Refseq: NM_032188
Protein Refseq: NP_115564
MIM: 609912
UniProt ID: Q9H7Z6
Chromosome Location: 16p11.2
Function: acetyltransferase activity; histone acetyltransferase activity; metal ion binding; methylated histone residue binding; protein binding; transcription factor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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