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Recombinant Human EPHX1, MYC/DDK-tagged

Cat.No. : EPHX1-390H
Product Overview : Recombinant Human EPHX1, fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
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  • Gene Information
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Description : Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Source : HEK293 Cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 52.8 kDa
Endotoxin : < 0.1 eu per 1 μg of the protein by the
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Storage : Store at -80 °C. Avoid repeated freeze-thaw cycles.
Concentration : >50 ug/ml as determined by BCA
Storage Buffer : 10% glycerol, 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) [ Homo sapiens ]
Official Symbol : EPHX1
Synonyms : EPHX1; epoxide hydrolase 1, microsomal (xenobiotic); EPHX; epoxide hydrolase 1; epoxide hydratase; MEH; EPOX; HYL1;
Gene ID : 2052
mRNA Refseq : NM_000120
Protein Refseq : NP_000111
UniProt ID : P07099
Chromosome Location : 1q42.1
Pathway : Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem;
Function : cis-stilbene-oxide hydrolase activity; epoxide hydrolase activity; hydrolase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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What is the impact of genetic polymorphisms in EPHX1 on drug metabolism and response to pharmacotherapy? 08/16/2022

Genetic variations in EPHX1 can influence drug metabolism, affecting individual responses to medications.

What are the mechanisms by which EPHX1 modulates inflammatory responses in the body? 08/16/2022

EPHX1 modulates inflammatory processes, potentially impacting the development and severity of inflammatory conditions.

How does EPHX1 (Epoxide Hydrolase 1) contribute to the metabolism of xenobiotics and endogenous compounds? 03/06/2021

EPHX1 is involved in metabolizing xenobiotics and endogenous compounds, playing a role in chemical detoxification.

How does EPHX1 influence the pathogenesis of respiratory diseases like COPD and asthma? 01/18/2021

EPHX1 impacts the development of respiratory diseases by modulating the metabolism of lung irritants.

How do alterations in EPHX1 expression or activity affect the risk and progression of chronic diseases? 06/25/2020

Changes in EPHX1 expression or function can alter disease risk, particularly in chronic conditions like cancer and cardiovascular diseases.

What role does EPHX1 play in the detoxification of environmental pollutants and carcinogens? 05/30/2019

EPHX1 helps detoxify environmental pollutants and carcinogens, reducing their harmful effects.

How does EPHX1 affect the metabolic processing of epoxyeicosatrienoic acids (EETs) and their role in cardiovascular health? 10/23/2018

EPHX1 processes EETs, important for cardiovascular function and blood pressure regulation.

Customer Reviews (3)

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Reviews
07/02/2022

    Efficient protein purification, delivers high yield and purity consistently.

    06/09/2020

      Dependable expertise in protein engineering, unmatched quality.

      03/26/2019

        Invaluable protein-protein interaction assays, integral to our research.

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