"PADI4" Related Products

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Recombinant Human PADI4, His-tagged

Cat.No.: PADI4-380H
Product Overview: Recombinant Human PADI4 (Ala2-Pro663) fused with an N-terminal 11 kDa fusion protein, a thrombin cleavage linker and 6­His tag at C­terminal, was expressed in E. coli.
Description: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
Source: E. coli
Species: Human
Tag: His
Predicted N Terminal: Inconclusive result, Met predicted. Protein identity confirmed by MS analysis of tryptic fragments
Formulation: Supplied as a 0.2 µm filtered solution in Sodium Acetate, NaCl, DTT, EDTA and Glycerol.
Bio-activity: Measured by its ability to catalyze the deimination of benzoyl-arginine ethyl ester. The specific activity is >1000 pmol/min/µg, as measured under the described conditions.
Molecular Mass: Predicted Molecular Mass: 87 kDa SDS-PAGE: 75-85 kDa, reducing conditions
Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.
Storage: Avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
Gene Name: PADI4 peptidyl arginine deiminase, type IV [ Homo sapiens (human) ]
Official Symbol: PADI4
Synonyms: PADI4; PAD; PAD4; PDI4; PDI5; PADI5; peptidyl arginine deiminase, type IV; protein-arginine deiminase type-4; HL-60 PAD; PADI-H protein; protein-arginine deiminase type IV; peptidyl arginine deiminase, type V; EC 3.5.3.15
Gene ID: 23569
mRNA Refseq: NM_012387
Protein Refseq: NP_036519
MIM: 605347
UniProt ID: Q9UM07
Chromosome Location: 1p36.13
Pathway: protein citrullination
Function: calcium ion binding; protein-arginine deiminase activity

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