Recombinant Human APOA4, His-tagged
Cat.No. : | APOA4-30H |
Product Overview : | Recombinant Human Apolipoprotein A4/APOA4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu21-Ser396) of Human APOA4 fused with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 |
AA Sequence : | EVSADQVATVMWDYFSQLSNNAKEA VEHLQKSELTQQLNALFQDKLGEVN TYAGDLQKKLVPFAT ELHERLAKDSEKLKEEIGKELEELR ARLLPHANEVSQKIGDNLRELQQRL EPYADQLRTQVNTQA EQLRRQLTPYAQRMERVLRENADSL QASLRPHADELKAKIDQNVEELKGR LTPYADEFKVKIDQT VEELRRSLAPYAQDTQEKLNHQLEG LTFQMKKNAEELKARISASAEELRQ RLAPLAEDVRGNLRG NTEGLQKSLAELGGHLDQQVEEFRR RVEPYGENFNKALVQQMEQLRQKLG PHAGDVEGHLSFLEK DLRDKVNSFFSTFKEKESQDKTLSL PELEQQQEQQQEQQQEQVQMLAPLE SVDHHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 1X PBS.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | APOA4 apolipoprotein A-IV [ Homo sapiens ] |
Official Symbol : | APOA4 |
Synonyms : | APOA4; apolipoprotein A-IV; apo-AIV; apoA-IV; apolipoprotein A4; MGC142154; MGC142156; |
Gene ID : | 337 |
mRNA Refseq : | NM_000482 |
Protein Refseq : | NP_000473 |
MIM : | 107690 |
UniProt ID : | P06727 |
Chromosome Location : | 11q23-qter |
Pathway : | Amyloids, organism-specific biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; Disease, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; |
Function : | antioxidant activity; cholesterol transporter activity; copper ion binding; contributes_to eukaryotic cell surface binding; lipid binding; lipid transporter activity; phosphatidylcholine binding; phosphatidylcholine-sterol O-acyltransferase activator activity; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
APOA4-2470H | Recombinant Human APOA4 Protein (21-396 aa), His-tagged | +Inquiry |
Apoa4-632M | Recombinant Mouse Apoa4 Protein, MYC/DDK-tagged | +Inquiry |
APOA4-628M | Recombinant Mouse APOA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
APOA4-1332M | Recombinant Mouse APOA4 Protein (21-395 aa), His-tagged | +Inquiry |
APOA4-375R | Recombinant Rat APOA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
ApoA4-68H | Native Human Apolipoprotein AIV | +Inquiry |
◆ Lysates | ||
APOA4-8788HCL | Recombinant Human APOA4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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