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Recombinant Human RYK, GST-tagged

Cat.No. : RYK-262H
Product Overview : Recombinant human RYK (255-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Description : RYK or receptor-like tyrosine kinase is an atypical member of the family of growth factor receptor protein tyrosine kinases. RYK differs from other receptor tyrosine kinases at a number of conserved residues in the activation and nucleotide binding domains. RYK has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. RYK is involved in stimulating Wnt signaling pathways such as the regulation of axon path finding.
Source : Sf9 insect cells using baculovirus
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tis-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~66 kDa
Purity : >90% by densitometry
Applications : Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : RYK receptor-like tyrosine kinase [ Homo sapiens ]
Official Symbol : RYK
Synonyms : RYK; receptor-like tyrosine kinase; JTK5A, JTK5A protein tyrosine kinase , RYK receptor like tyrosine kinase; tyrosine-protein kinase RYK; D3S3195; JTK5; RYK1; hydroxyaryl-protein kinase; JTK5A protein tyrosine kinase; RYK receptor-like tyrosine kinase; JTK5A;
Gene ID : 6259
mRNA Refseq : NM_001005861
Protein Refseq : NP_001005861
MIM : 600524
UniProt ID : P34925
Chromosome Location : 3q22.1
Pathway : Wnt signaling network, organism-specific biosystem;
Function : ATP binding; Wnt-protein binding; frizzled binding; nucleotide binding; protein binding; NOT protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; transmembrane signaling receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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