Active Recombinant Mouse Ncam1, His tagged

• Cat.No.: Ncam1-112M
• Product Overview: Recombinant Mouse Ncam1 (Met1-Thr711) fused with?6-His tag at C-terminal, was expressed in Mouse?NSO?Cells.

Specification

• Description: Neural Cell Adhesion Molecule?(NCAM, also thecluster of differentiationCD56) is a homophilic binding glycoprotein expressed on the surface of?neurons,?glia,skeletal muscle?and?natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion,?neurite outgrowth, synaptic plasticity, and learning and memory.
• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Leu20
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of Neuro?2A mouse neuroblastoma cells. When 5 x 104 cells/well are added to mouse NCAM-1 coated plates (25 μg/mL with 100 μL/well), >20% will adhere after 1 hour incubation at 37 °C.
• Molecular Mass: 77.4 kDa
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: Ncam1 neural cell adhesion molecule 1 [ Mus musculus ]
• Official Symbol: Ncam1
• Synonyms: NCAM1; neural cell adhesion molecule 1; N-CAM-1; CD56; Ncam; E-NCAM; NCAM-1
• Gene ID: 17967
• mRNA Refseq: NM_001081445
• Protein Refseq: NP_001074914
• Pathway: Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem
• Function: LRR domain binding; heparin binding; phosphatase binding