Native Human ApoC-III
Cat.No. : | ApoC-III-3559H |
- Specification
- Gene Information
- Related Products
Description : | Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. |
Source : | Human plasma |
Species : | Human |
Form : | Supplied as a liquid in 10mM NH4HCO3, pH 7.4. |
Molecular Mass : | 875 kDa |
Purity : | >95% pure by SDS PAGE |
Notes : | Small volumes of ApoC-III native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | APOC3 apolipoprotein C-III [ Homo sapiens ] |
Official Symbol : | APOC3 |
Synonyms : | APOC3; apolipoprotein C-III; apo-CIII; apoC-III; apolipoprotein C3; HALP2; APOCIII; MGC150353; |
Gene ID : | 345 |
mRNA Refseq : | NM_000040 |
Protein Refseq : | NP_000031 |
MIM : | 107720 |
UniProt ID : | P02656 |
Chromosome Location : | 11q23-qter |
Pathway : | Chylomicron-mediated lipid transport, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem; |
Function : | cholesterol binding; enzyme regulator activity; high-density lipoprotein particle receptor binding; lipase inhibitor activity; phospholipid binding; |
Products Types
◆ Recombinant Protein | ||
APOC3-2235C | Recombinant Cynomolgus Monkey APOC3 Protein (21-99 aa), His-SUMOSTAR-tagged | +Inquiry |
APOC3-1333R | Recombinant Rat APOC3 Protein (21-101 aa), His-tagged | +Inquiry |
Apoc3-1126M | Recombinant Mouse Apoc3 Protein, His-SUMO-tagged | +Inquiry |
APOC3-635M | Recombinant Mouse APOC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Apoc3-818M | Recombinant Mouse Apoc3 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
APOC3-361H | Native Human Apolipoprotein C-III | +Inquiry |
APOC3-27333TH | Native Human APOC3 | +Inquiry |
APOC3-669H | Native Human APOC3 protein | +Inquiry |
◆ Lysates | ||
APOC3-8782HCL | Recombinant Human APOC3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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