Active Recombinant Human MAK, GST-tagged

• Cat.No.: MAK-35H
• Product Overview: Recombinant full-length human MAK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: MAK or male germ cell-associated kinase is a serine/threonine protein kinase related to kinases involved in cell cycle regulation which is expressed almost exclusively in the testis, primarily in germ cells. MAK plays an important role in spermatogenesis. MAK is also required for retinal photoreceptor survival. MAK is a regulator of ciliary length, as a cause of retinitis pigmentosa.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 40 nmol/min/mg
• Molecular Mass: ~78 kDa
• Applications: Kinase Assay, Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1ug/ul

Gene Information

• Gene Name: MAK male germ cell-associated kinase [ Homo sapiens ]
• Official Symbol: MAK
• Synonyms: MAK; male germ cell-associated kinase; serine/threonine-protein kinase MAK; dJ417M14.2; serine/threonine protein kinase MAK; male germ cell-associated kinase retinal-enriched isoform; RP62
• Gene ID: 4117
• mRNA Refseq: NM_001242385
• Protein Refseq: NP_001229314
• MIM: 154235
• UniProt ID: P20794
• Chromosome Location: 6q22
• Pathway: Coregulation of Androgen receptor activity, organism-specific biosystem
• Function: ATP binding; ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transcription coactivator activity; transferase activity, transferring phosphorus-containing groups