Cat.No.: | PI4K2A-1350HCL |
Description: | Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]). |
Species: | Human |
Size: | 100 ul |
Storage Buffer: | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications: | Western Blot; |
Gene Name: | PI4K2A phosphatidylinositol 4-kinase type 2 alpha [ Homo sapiens ] |
Official Symbol: | PI4K2A |
Synonyms: | PI4K2A; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; DKFZP761G1923; PI4KII; PIK42A; phosphatidylinositol 4-kinase type II-alpha; phosphatidylinositol 4-kinase type II (PI4KII); RP11-548K23.6; DKFZp761G1923; |
Gene ID: | 55361 |
mRNA Refseq: | NM_018425 |
Protein Refseq: | NP_060895 |
MIM: | 609763 |
UniProt ID: | Q9BTU6 |
Chromosome Location: | 10q24 |
Pathway: | 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; |
Function: | 1-phosphatidylinositol 4-kinase activity; ATP binding; kinase activity; magnesium ion binding; nucleotide binding; transferase activity; |
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