Recombinant Human CBR3, MYC/DDK-tagged

• Cat.No.: CBR3-185H
• Product Overview: Recombinant Human CBR3, fused with C-terminal MYC/DDK, was expressed in HEK293 cells

Specification

• Description: Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
• Source: HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 Mm glycine, 10% glycerol.
• Molecular Mass: 30.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CBR3 carbonyl reductase 3 [ Homo sapiens ]
• Official Symbol: CBR3
• Synonyms: hCBR3; SDR21C2; HEL-S-25; carbonyl reductase [NADPH] 3; carbonyl reductase (NADPH) 3; epididymis secretory protein Li 25; NADPH-dependent carbonyl reductase 3; short chain dehydrogenase/reductase family 21C, member 2
• Gene ID: 874
• mRNA Refseq: NM_001236
• Protein Refseq: NP_001227
• MIM: 603608
• UniProt ID: O75828
• Chromosome Location: 21q22.2
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem
• Function: 3-keto sterol reductase activity; NADPH binding; carbonyl reductase (NADPH) activity