Native Human Hemopexin

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Native Human Hemopexin

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Cat.No. : HPX-207H
Description : Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.
Source : Human Plasma
Species : Human
Form : Lyophilized
Molecular Mass : MW: 57,000
Endotoxin : <1.0 eu/mg by fluorogenic assay, lonza,>
Purity : >= 95% by SDS-PAGE
Usage : For research use only.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : -20°C
Storage Buffer : 11.9 mM phosphate, 137 mM CaCl, 2.7 mM KCI, pH 7.4
Gene Name : HPX hemopexin [ Homo sapiens ]
Official Symbol : HPX
Synonyms : HPX; hemopexin; beta-1B-glycoprotein; HX; FLJ56652;
Gene ID : 3263
mRNA Refseq : NM_000613
Protein Refseq : NP_000604
MIM : 142290
UniProt ID : P02790
Chromosome Location : 11p15.5-p15.4
Function : binding; heme transporter activity; metal ion binding; protein binding;

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