Recombinant Human Glycine N-methyltransferase, His tagged
Cat.No. : | GNMT-119H |
Product Overview : | Recombinant human GNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques,34.9kDa (315aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | GNMT -119H |
Description : | Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol |
Purity : | > 95% by SDS - PAGE |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | GNMT glycine N-methyltransferase [ Homo sapiens ] |
Synonyms : | glycine N-methyltransferase; glycine N-methyltransferase; EC 2.1.1.20; OTTHUMP00000016412; GNMT |
Gene ID : | 27232 |
mRNA Refseq : | NM_018960 |
Protein Refseq : | NP_061833 |
MIM : | 606628 |
UniProt ID : | Q14749 |
Chromosome Location : | 6p12 |
Pathway : | Glycine, serine and threonine metabolism |
Function : | folic acid binding ; glycine N-methyltransferase activity; glycine binding; methyltransferase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
GNMT-5086H | Recombinant Human GNMT Protein, GST-tagged | +Inquiry |
GNMT-2267R | Recombinant Rat GNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
GNMT-232H | Active Recombinant Human GNMT Protein, His-tagged, Bioactivity Validated | +Inquiry |
Gnmt-1041M | Recombinant Mouse Gnmt Protein, MYC/DDK-tagged | +Inquiry |
GNMT-577H | Recombinant Human GNMT Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GNMT-5844HCL | Recombinant Human GNMT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All GNMT Products
Required fields are marked with *
My Review for All GNMT Products
Required fields are marked with *
0
Inquiry Basket