Recombinant Human Synuclein, Alpha (Non A4 Component of Amyloid Precursor), 1-95

Cat. No. : SNCA-295H
Product Overview : Recombinant Human α-Synuclein protein produced in E.Coli encodes 95 (1-95) amino acids and has a molecular mass of 9.3 kDa.
Description : A deletion mutant ofa-synuclein (amino acids 1-95), which contains the N-terminal amphipathic domain and NAC region. a-synuclein 1-95 was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by using conventional column chromatography techniques.
Source : E.coli.
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl.
Molecular Weight : 9.3 kDa (95 aa).
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by BCA assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : SNCA
Synonyms : SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; MGC110988; alpha-synuclein, isoform NACP140; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; alpha-synuclein; OTTHUMP00000161559; OTTHUMP00000161561; non A-beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor); Synuclein, alpha (non-Abeta component of Alzheimer"s disease amyloid precursor protein: NACP).
Gene ID : 6622
mRNA Refseq : NM_000345.3
Protein Refseq : NP_000336.1
MIM : 163890
UniProt ID : P37840
Chromosome Location : 4q21
Pathway : Alzheimer"s disease;Neurodegenerative Disorders;Parkinson"s disease.
Function : Hsp70 protein binding;alpha-tubulin binding;dynein binding;histone binding;kinesin binding;tau protein binding;transferrin transmembrane transporter activity.

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