Cat. No. : | SNCA-295H |
Product Overview : | Recombinant Human α-Synuclein protein produced in E.Coli encodes 95 (1-95) amino acids and has a molecular mass of 9.3 kDa. |
Description : | A deletion mutant ofa-synuclein (amino acids 1-95), which contains the N-terminal amphipathic domain and NAC region. a-synuclein 1-95 was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by using conventional column chromatography techniques. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl. |
Molecular Weight : | 9.3 kDa (95 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by BCA assay). |
Sequence : | MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFV |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | SNCA |
Synonyms : | SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; MGC110988; alpha-synuclein, isoform NACP140; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; alpha-synuclein; OTTHUMP00000161559; OTTHUMP00000161561; non A-beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor); Synuclein, alpha (non-Abeta component of Alzheimer"s disease amyloid precursor protein: NACP). |
Gene ID : | 6622 |
mRNA Refseq : | NM_000345.3 |
Protein Refseq : | NP_000336.1 |
MIM : | 163890 |
UniProt ID : | P37840 |
Chromosome Location : | 4q21 |
Pathway : | Alzheimer"s disease;Neurodegenerative Disorders;Parkinson"s disease. |
Function : | Hsp70 protein binding;alpha-tubulin binding;dynein binding;histone binding;kinesin binding;tau protein binding;transferrin transmembrane transporter activity. |
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