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Recombinant Human MGEA5, MYC/DDK-tagged

Cat.No.: MGEA5-86H
Product Overview: Recombinant Human MGEA5, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications.
Source: HEK293 cells
Species: Human
Tag: MYC/DDK
Molecular Mass: 102.7 kDa
Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: MGEA5 meningioma expressed antigen 5 (hyaluronidase) [ Homo sapiens (human) ]
Official Symbol: MGEA5
Synonyms: MGEA5; meningioma expressed antigen 5 (hyaluronidase); bifunctional protein NCOAT; MEA5; NCOAT; nuclear cytoplasmic O GlcNAcase and acetyltransferase; OGA; O-GlcNAcase; hyaluronidase in meningioma; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase and acetyltransferase; FLJ11229; FLJ23355; KIAA0679
Gene ID: 10724
mRNA Refseq: NM_012215
Protein Refseq: NP_036347
MIM: 604039
UniProt ID: O60502
Chromosome Location: 10q24.1-q24.3
Pathway: protein O-[N-acetyl]-glucosylation
Function: beta-N-acetylglucosaminidase activity; histone acetyltransferase activity; hyalurononglucosaminidase activity

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