Recombinant Human MGEA5, MYC/DDK-tagged MGEA5-86H

Recombinant Human MGEA5, MYC/DDK-tagged


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Recombinant Human MGEA5, MYC/DDK-tagged

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Cat.No. : MGEA5-86H
Product Overview : Recombinant Human MGEA5, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications.
Source : HEK293 cells
Species : Human
Molecular Mass : 102.7 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : MGEA5 meningioma expressed antigen 5 (hyaluronidase) [ Homo sapiens (human) ]
Official Symbol : MGEA5
Synonyms : MGEA5; meningioma expressed antigen 5 (hyaluronidase); bifunctional protein NCOAT; MEA5; NCOAT; nuclear cytoplasmic O GlcNAcase and acetyltransferase; OGA; O-GlcNAcase; hyaluronidase in meningioma; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase and acetyltransferase; FLJ11229; FLJ23355; KIAA0679
Gene ID : 10724
mRNA Refseq : NM_012215
Protein Refseq : NP_036347
MIM : 604039
UniProt ID : O60502
Chromosome Location : 10q24.1-q24.3
Pathway : protein O-[N-acetyl]-glucosylation
Function : beta-N-acetylglucosaminidase activity; histone acetyltransferase activity; hyalurononglucosaminidase activity

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