"RCVRN" Related Products

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Recombinant Human Recoverin

Cat. No.: RCVRN-191H
Product Overview: Recombinant Human Recoverin produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 200 amino acids and has a molecular mass of 23 kDa.
Description: Recoverin is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome.
Source: E.Coli.
Amino Acid Sequence: MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKNEVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA.
Physical Appearance: Sterile filtered clorless solution.
Formulation: The protein (1mg/ml) contains 20 mM Tris pH 8.0, 1 mM EDTA, 2mM MgCl2and 10% Glycerol.
Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Gene Name: RCVRN recoverin [ Homo sapiens ]
Synonyms: RCVRN; RCV1; recoverin; RCV-1; Cancer-associated retinopathy protein; Protein CAR; cancer associated retinopathy antigen
Gene ID: 5957
mRNA Refseq: NM_002903
Protein Refseq: NP_002894
MIM: 179618
UniProt ID: P35243
Chromosome Location: 17p13
Function: calcium ion binding; calcium sensitive guanylate cyclase activator activity

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