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Recombinant Human SSB

Cat.No. : SSB-150H
Product Overview : Recombinant Human LA/SS-B produced inSF9is a single, glycosylated, polypeptide chain having a calculated molecular mass of 47.6 kDa, is fused to a hexahistidine purification tag. The LA/SS-B is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : SSB-150H
Discription : La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus.
Source : Sf9 insect cells.
Physical Appearance : Sterile Filtered clear solution.
Formulation : The protein solution contains 20mM HEPES, pH 7.5, 400mM NaCl, 20% Glycerol.
Purity : Greater than 95.0% as determined by SDS-PAGE
Immunological functions : 1. Binds IgG-type human auto-antibodies. 2. Standard ELISA test (checker-board analysis of positive/negative sera panels, immuno-dot test).
Coating concentration : 0.6-1.1 µg/ml (depending on the type of ELISA plate and coating buffer).Suitable for biotinylation and iodination.
Stability : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Gene Name : SSB Sjogren syndrome antigen B (autoantigen La) [ Homo sapiens ]
Synonyms : Sjogren syndrome antigen B (autoantigen La); La; LARP3; SSB; autoantigen La; SS-B/La protein; OTTHUMP00000204778; La ribonucleoprotein domain family, member 3; SS-B; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen
Gene ID : 6741
mRNA Refseq : NM_003142
Protein Refseq : NP_003133
MIM : 109090
UniProt ID : P05455
Pathway : Systemic lupus erythematosus
Function : mRNA binding; nucleotide binding; protein binding; tRNA binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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