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Recombinant Human Growth Differentiation Factor 10

Cat. No.: GDF10-474H
Product Overview: Recombinant GDF10 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.5 kDa (111aa).
Description: GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletalmorphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
Source: E.coli.
Form: Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: GDF10 growth differentiation factor 10 [ Homo sapiens ]
Synonyms: GDF10; growth differentiation factor 10; BMP3B; BMP-3b;bone morphogenetic protein 3B; Bone morphogenetic protein 3b; Growth/differentiation factor 10; GDF-10; Bone-inducing protein
Gene ID: 2662
mRNA Refseq: NM_004962
Protein Refseq: NP_004953
MIM: 601361
UniProt ID: P55107
Chromosome Location: 10q11.22
Function: cytokine activity; growth factor activity

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