||Recombinant GDF10 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.5 kDa (111aa).
||GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletalmorphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
||Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.
||> 95% by SDS – PAGE.
||1 mg/ml (determined by Bradford assay).
|Sequences Of Amino Acids:
||MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R.
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.