Active Recombinant Mouse ACVR2B protein(Met1-Thr134), His&hFc-tagged
Cat.No. : | ACVR2B-198M |
Product Overview : | Recombinant Mouse ACVR2B (NP_031423.1)(Met 1-Thr 134) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | C-His&hFc |
Protein length : | Met1-Thr134 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its ability to bind biotinylated Human INHBA-his in functional ELISA. 2. Measured by its ability to bind biotinylated mouse INHBA-his in functional ELISA. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell prolifeRation. The ED50 for this effect is typically 10-50 ng/mL in the presence of 10 ng/mL recombinant Activin A. |
Molecular Mass : | The recombinant mouse ACVR2B/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 364 amino acids and has a predicted molecular mass of 41 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B/Fc monomer is approximately 60-65 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Acvr2b activin receptor IIB [ Mus musculus ] |
Official Symbol : | ACVR2B |
Synonyms : | ACVR2B; activin receptor IIB; activin receptor type-2B; ACTR-IIB; activin receptor type IIB; ActRIIB; |
Gene ID : | 11481 |
mRNA Refseq : | NM_007397 |
Protein Refseq : | NP_031423 |
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◆ Lysates | ||
ACVR2B-734CCL | Recombinant Cynomolgus ACVR2B cell lysate | +Inquiry |
ACVR2B-2724HCL | Recombinant Human ACVR2B cell lysate | +Inquiry |
ACVR2B-2540MCL | Recombinant Mouse ACVR2B cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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