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Native Human APCS

Cat.No.: APCS-31189TH
Product Overview: Full length native Human Serum Amyloid P purified from normal Human serum/plasma, MWt 250kDa.
Description: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Protein length: 204 amino acids
Molecular Weight: 250.000kDa
Form: Liquid
Storage buffer: Preservative: 0.09% Sodium AzideConstituents: 0.14M Sodium chloride, 0.01M EDTA, 0.01M Tris, pH 8.0
Storage: Store at +4°C.
Gene Name: APCS amyloid P component, serum [ Homo sapiens ]
Official Symbol: APCS
Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP;
Gene ID: 325
mRNA Refseq: NM_001639
Protein Refseq: NP_001630
MIM: 104770
Uniprot ID: P02743
Chromosome Location: 1q21-q23
Pathway: Amyloids, organism-specific biosystem;
Function: metal ion binding; sugar binding; unfolded protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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