Native Human BCHE
Cat.No. : | BCHE-26067TH |
Product Overview : | Full length native Human Butyrylcholinesterase from Human plasma/serum. Amino acids 29-602, Predicted MWt 68kDa. |
- Specification
- Gene Information
- Related Products
Description : | Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. |
Protein length : | 574 amino acids |
Molecular Weight : | 65.000kDa |
Tissue specificity : | Detected in blood plasma (at protein level). Present in most cells except erythrocytes. |
Biological activity : | Butyrylcholinesterase enzyme assay: One unit of Butyrylcholinesterase will hydrolyse 1.0μ mole of Butyrylcholine per min at pH 8.0 at 37°C. |
Form : | Lyophilised:Use of a phosphate buffer pH >7.0 containing 0.15M NaCl is recommended. |
Storage buffer : | Preservative: NoneConstituents: 0.02M Ammonium bicarbonate. May contain traces of buffer salts. |
Storage : | Store at +4°C. |
Sequence Similarities : | Belongs to the type-B carboxylesterase/lipase family. |
Gene Name : | BCHE butyrylcholinesterase [ Homo sapiens ] |
Official Symbol : | BCHE |
Synonyms : | BCHE; butyrylcholinesterase; CHE1, cholinesterase 1; cholinesterase; E1; |
Gene ID : | 590 |
mRNA Refseq : | NM_000055 |
Protein Refseq : | NP_000046 |
Uniprot ID : | P06276 |
Chromosome Location : | 3q26.1-q26.2 |
Pathway : | Diabetes pathways, organism-specific biosystem; Irinotecan Pathway, organism-specific biosystem; Synthesis, Secretion, and Deacylation of Ghrelin, organism-specific biosystem; |
Function : | acetylcholinesterase activity; acetylcholinesterase activity; acetylcholinesterase activity; beta-amyloid binding; carboxylesterase activity; |
Products Types
◆ Recombinant Protein | ||
BCHE-574H | Recombinant Human BCHE Protein, His-tagged | +Inquiry |
BCHE-435H | Recombinant Human BCHE Protein, His (Fc)-Avi-tagged | +Inquiry |
Bche-575R | Recombinant Rat Bche Protein, His-tagged | +Inquiry |
Bche-910M | Active Recombinant Mouse Bche protein(Met1-Leu603), His-tagged | +Inquiry |
Bche-984M | Recombinant Mouse Bche Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
BCHE-8E | Active Native Equine Butyrylcholine esterase | +Inquiry |
BCHE-157H | Active Native Horse Serum Butyrylcholinesterase | +Inquiry |
BCHE-5291H | Native Human Butyrylcholinesterase | +Inquiry |
◆ Lysates | ||
BCHE-2196HCL | Recombinant Human BCHE cell lysate | +Inquiry |
BCHE-2286MCL | Recombinant Mouse BCHE cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0133 | Butyrylcholinesterase Fluorometric Detection Kit | +Inquiry |
Kit-2349 | Butyrylcholinesterase Activity Kit (Colorimetric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket