"CDC37" Related Products

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Recombinant Human CDC37, His-tagged

Cat.No. : CDC37-26222TH
Product Overview : Recombinant full length Human Cdc37 with an N terminal His tag; 388 amino acids with tag, Predicted MWt 45.71 kDa.
Description : The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Protein length : 378 amino acids
Conjugation : HIS
Molecular Weight : 45.710kDa inclusive of tags
Source : E. coli
Form : Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the ce
Storage buffer : Preservative: NoneConstituents: 50mM Sodium chloride, 20mM Tris, pH 7.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MKHHHHHHASMVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
Sequence Similarities : Belongs to the CDC37 family.
Gene Name : CDC37 cell division cycle 37 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : CDC37
Synonyms : CDC37; cell division cycle 37 homolog (S. cerevisiae); CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog (S. cerevisiae); hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37; S. cerevisiae; homolog); CDC37
Gene ID : 11140
mRNA Refseq : NM_007065
Protein Refseq : NP_008996
MIM : 605065
Uniprot ID : Q16543
Chromosome Location : 19p13.2
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : Hsp90 protein binding; heat shock protein binding; protein binding; unfolded protein binding;

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