"DDIT4" Related Products


Recombinant Human DDIT4

Cat.No.: DDIT4-28311TH
Product Overview: Recombinant full length protein, corresponding to amino acids 1-232 of Human DDIT4
Description: DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level.
Source: E. coli
Tissue specificity: Broadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level).
Form: Liquid
Purity: Purified via His tag
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the DDIT4 family.
Gene Name: DDIT4 DNA-damage-inducible transcript 4 [ Homo sapiens ]
Official Symbol: DDIT4
Synonyms: DDIT4; DNA-damage-inducible transcript 4; DNA damage-inducible transcript 4 protein; Dig2; FLJ20500; HIF 1 responsive RTP801; REDD 1; REDD1; RTP801;
Gene ID: 54541
mRNA Refseq: NM_019058
Protein Refseq: NP_061931
MIM: 607729
Uniprot ID: Q9NX09
Chromosome Location: 10q22.1
Pathway: Direct p53 effectors, organism-specific biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, conserved biosystem;
Function: 14-3-3 protein binding;

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