Recombinant Human EPHA4
Cat.No. : | EPHA4-26439TH |
Product Overview : | Recombinant fragment corresponding to amino acids 610-887 of human Eph receptor A4 with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system, 58kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
Tissue specificity : | Ubiquitous. |
Biological activity : | Specific activity of Eph receptor A4 was determined to be 83 nmol/min/mg as per activity assay protocol. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.Contains 2 fibronectin type-III domains.Contains 1 protein kinase domain.Contains 1 SAM (sterile alpha motif) domain. |
Gene Name : | EPHA4 EPH receptor A4 [ Homo sapiens ] |
Official Symbol : | EPHA4 |
Synonyms : | EPHA4; EPH receptor A4; EphA4 , TYRO1; ephrin type-A receptor 4; Hek8; |
Gene ID : | 2043 |
mRNA Refseq : | NM_004438 |
Protein Refseq : | NP_004429 |
MIM : | 602188 |
Uniprot ID : | P54764 |
Chromosome Location : | 2q36.3 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHA forward signaling, organism-specific biosystem; EphrinA-EPHA pathway, organism-specific biosystem; |
Function : | ATP binding; DH domain binding; GPI-linked ephrin receptor activity; PH domain binding; ephrin receptor binding; |
Products Types
◆ Recombinant Protein | ||
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EPHA4-1309R | Recombinant Rhesus Macaque EPHA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHA4-3384H | Active Recombinant Human EPHA4 Protein, GST-tagged | +Inquiry |
EPHA4-0977H | Recombinant Human EPHA4 Protein (E252-V986), Tag Free | +Inquiry |
Epha4-7440R | Active Recombinant Rat Epha4 protein(Met1-Thr547), His-tagged | +Inquiry |
◆ Lysates | ||
EPHA4-1192CCL | Recombinant Cynomolgus EPHA4 cell lysate | +Inquiry |
EPHA4-001HCL | Recombinant Human EPHA4 cell lysate | +Inquiry |
EPHA4-1933HCL | Recombinant Human EPHA4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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